Abstract
Objectives: To determine the role of heart fatty acid-binding protein in early detection of non-ST-elevation myocardial infarction and its comparison with two other cardiac markers.
Methods: The cross-sectional study was conducted at Abbasi Shaheed Hospital, Karachi, from June 2012 to June 2014, and comprised patients presenting at the emergency department within two hours of chest pain and who were subsequently referred to the cardiology department with a provisional diagnosis of either unstable angina or non-ST-elevation myocardial infarction. Relevant history was taken on a specific proforma and electrocardiogram as well as routine investigations were done in the emergency department. Blood samples from the subjects were tested for the diagnosis of myocardial infarction through detection of heart fatty acid-binding protein, Troponin-I and Creatine kinase-myocardial band. Sensitivity and specificity of the three markers were calculated keeping coronary angiography as the gold standard. Data was analysed using SPSS 17.
Results: Out of 250 patients, 153(61.2%) were males. The overall mean age was 54.45±13.92 years. Sensitivity and specificity of heart fatty acid-binding protein were 80.6% and 78.5% (p<0.05), for Troponin-I, 37.7% and 75% (p>0.05), and for Creatine Kinase-myocardial band, 29.5% and 67.8% (p>0.05).
Conclusion: Heart fatty acid-binding protein was found to be a good diagnostic tool for the detection of non-ST-elevation myocardial infarction.
Key Words: Non ST-elevation myocardial infarct, Cardiac markers, Heart fatty acid-binding protein, Troponin-I, Creatine kinase isoenzyme MB, Angiography. Continuous...
Interaction of nickel with taurine was investigated by different spectrophotometric methods. The results, thus obtained were interpreted in terms of complex formation between nickel and taurine in the ration 1:2. Further evidence to this effect was provided by conductometric studies. Moreover, the effect of pH on the nature of nickel ion binding to taurine was also studied spectrophotometrically.
Mustafa Kamal abolished the institution of Khilafat in 1924, but the Sargodha district Khilafat Committee continued its functioning. Peers of Sial Sharif and Bugvis of Bhera played the leading role, while pro-British feudal lords supported the government. Khilafat conferences were held in which high-level Khilafat leaders participated and addressed. Samarna-Fund was collected, and a sum of Rs 9600 was submitted to the Punjab Khilafat Committee. Sialvi and Bugvi visited different towns and villages and conveyed the Khilafat message in simple words. Bugvi was arrested and sent to prison for one and a half year. While on the arrest of Peer of Sial-Sharif, the Muslims of Soon Valley began to offer arrest every day. From the Khilafat movement, Muslims of Sargodha enhanced their awareness and gained experience. They utilized it in Pakistan Movement 1940-47 and received prominent status in any district of Punjab outside Lahore. They challenged their feudal lords of past and rulers of present and, as a powerful factor, won their share in freedom.
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