The article showed the results of ultrasonic assessment of topographic and functional diaphragm indices in patients with severe diffuse emphysema. They passed the selection for lung volume reduction surgery. The comparison of diaphragm indices was presented in patients with diffuse emphysema and control group of healthy volunteers. Dynamics of diaphragm condition was studied after surgical treatment. There wasn’t noted any statistical difference of diaphragm topographic indices as compared with the control group. There wasn’t shown a correlation between respiratory function indices and functional diaphragm indices, but it was noted a positive tendency in characteristics during quiet breathing.
Chronic obstructive pulmonary disease (COPD) is one of important problems of public healthcare. The aim of the present study was to investigate effect of beclomethazone on endothelial function (endothelin-1 level and results of Celermajer's test) and ultrasound parameters of pulmonary and central circulation in 42 COPD patients. Endothelium dysfunction was found in 66% of patients. It improved after antiinflammatory treatment. The improvement in myocardial diastolic function and decrease in systolic pulmonary artery pressure were revealed after 3-month beclomethazone therapy.
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