Under real conditions adolescents are influenced by a complex of environmental factors that determine the relevance of the search for quantitative indices of the health status under the action of environmental factors. The article shows that in conditions of complex influence of environmental factors in adolescents in the state of health, deviations are noted at the level of changes in physiological status characterized by disorganization of the functioning of the central nervous, cardiovascular and respiratory systems, the inter-systemic connections of which increase with the elevating dose of factors. On the basis of the mathematical analysis, an integral index of physiological status was determined - the index of physiological imbalance (IFD), which in adolescents subjected to a high anthropogenic load was by 1.7 times higher than in adolescents living in an area where the anthropogenic load was 1.4 times lower and correspondingly was 2.85 units and 1.60 units, which indicated to the tension of the processes of adaptation of the organism to a complex of environmental factors on the basis of the gradation scale of adaptation reactions developed by the authors, depending on the quantitative characteristics of the index of physiological imbalance.
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