Inconsistencies in feeding level of dairy cattle to their feed needs leads to various metabolic diseases, including ketosis. The purpose of our work is to study changes in the metabolism of both sexually mature representatives of dairy cattle and young animals obtained from them. The article states the following causal factors of ketosis occurrence in cows: excessive amount of fat substances, imbalance of various chemical elements in feeding diet. The pathology of carbohydrate-fat metabolism during ketosis in cows was characterized by a significant change in blood biochemical parameters, namely, an increase in triglycerides (up to 0.7 ± 0.07 mmol/l), cholesterol (up to 2.7 ± 0.15 mmol/l), non-esterified fatty acids (up to 1.93 ± 0.19 mmol/l), KET (up to 2.4 ± 0.18 mmol/l), low glucose concentration (up to 1.07 ± 0.12 mmol/l) and alkaline reserve (up to 17.8 ± 1.5 mmol/l). Low level of triglycerides, cholesterol, and alkaline reserve, as well as high values of non-esterified fatty acids, KET, and glucose characterize the exchange in calves from cows with ketosis relative to calves born by cows without metabolic pathology.
Under present-day conditions of market economy, the requirements to the quality and quantity of livestock products increase significantly, and this leads to significant intensification of production and, as a consequence, to the development of metabolic disorders including ketosis in highly productive cows. The research goal was to study protein and mineral metabolism in ketotic cows before and after calving. The studies were conducted on the Training Farm «Prigorodnoye» in the City of Barnaul in autumn and winter in comparable Black-Pied cows. Two groups of cows were formed: the trial group consisted of ketotic cows; the control group consisted of apparently healthy cows. These cows underwent clinical and biochemical examination. The biochemical study of blood determined the following: total protein, albumins, alpha-globulins, beta-globulins, gamma-globulins, total calcium, inorganic phosphorus and ketone bodies. The biochemical blood tests were run 4 times: 2 months and 1 month before calving, and in 10 days and in 1 month after calving. It was found that the change of protein metabolism indices in ketotic cows showed a profound disorder of the protein synthesis function of liver both before and after calving. The level of total calcium in the blood of ketotic cows was characterized by lower values as compared to that in healthy comparable cows. At the same time, the dynamics of inorganic phosphorus concentration change did not have significant differences between ketotic and healthy cows. Total calcium content in ketotic cows increased one month before calving while in apparently healthy cows this index increased after calving only. The concentration of ketone bodies in the blood of ketotic cows was significantly higher than that of apparently healthy cows throughout the study.
Newcastle disease affects birds of different breeds and ages (turkeys, quails, guinea fowls, chickens). Given the possibility of spreading the disease by birds of other species, including migratory birds, it makes more sense to immunize chickens during their long-distance migration. The main measure of disease prevention remains its competent specific prevention with the use of live and inactivated vaccines, as the specialists of the Khankai branch of the Khorol Veterinary Station for animal diseases control told the public. The only way to protect against the disease is to vaccinate all types of poultry.
Among the main tasks of cattle breeding is creation of conditions for obtaining healthy young animals, which will ensure high level of productivity in the future. Nowadays, interest in probiotic products is growing in countries around the world. Probiotics help to reduce diseases of livestock, improve digestion, metabolism, increase animal productivity, and maintain the immunological status. Vetom series probiotics are widely used in this industry. These products have an extensive range of actions, one of which is correction of immunobiochemical status. The aim of our study was to study the effect of Vetom 1.2 probiotics on immunological status of blood and milk. Scientific and economic experiment was carried out at AO "Uchkhoz" Prigorodnoe ", Barnaul, on black-and-white cows in the autumn-winter period. The manufacturer of "Vetom 1.2" probiotic preparation is OOO NPF "Research Center", Novosibirsk Region, Koltsovo v. When analyzing the results of the studies, we found: 1. Increase of parameters during the study period: carotene by 27.4%, retinol and tocopherol by 26.5% and 16.2%, respectively, gamma globulin by 15.8%, albumin by 10 .6%. 2. Increase of immunoglobulins in blood serum of cows in the experimental group compared to the control group: albumin by 14.4%; alpha, beta, gamma globulin by 16.3%, 13.7%, 17.8%, respectively. 3. It was found that the level of immunoglobulins in colostrum was higher by 31.4% in the experimental group of cows on the first day of lactation, on the second day by 14.1% compared to the control group. Based on the obtained results, the following conclusions were made: 1. "Vetom 1.2" has a positive effect on dynamics of immunological status of cow blood. 2. The probiotics helps to increase the level of immunoglobulins in the colostrum of cows.
The active development and intensification of animal husbandry, with technological errors (abnormal operation, unbalanced diets, keeping conditions, and others), increases the risk of the occurrence of a variety of metabolic diseases (ketosis, osteodystrophy, hepatosis). The study aimed to investigate the metabolic changes in dairy cows during the “close to calving” period of acetonemia. The authors researched cows of black-motley breed based on the joint-stock company of educational and experimental farm “Prigorodnoye”, Barnaul. The research was carried out four times: 2 and 1 month before calving, and 10 days and 1 month after calving. During the study, clinical and biochemical examination of the selected animals was carried out. The authors found that in ketosis cows have increased respiratory rate and heart rate. The authors also noted signs of osteodystrophy and rumen hypotonia. In cows with ketosis, the level of total calcium was below the physiological limits during the whole study. The authors observed an increase in total calcium concentration one month and ten days after calving, after which this concentration decreased. Inorganic phosphorus concentrations decreased one month before calving and increased sharply after calving. Hypoglycemia and acidosis were also noted by the authors. Acetone bodies decreased by calving and increased after calving. Triglyceride levels increased before calving and exceeded physiological values one month before calving. After calving, triglyceride concentration decreased sharply. The concentration of cholesterol in the blood of cows rose during the whole period of the study and its level was within the physiological norm.
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