Reaction of alkoxyhalogenation 3-organyloxy-1-propenes with N-bromosuccinimide (or iodine) in dimethylacetylenecarbinol medium proceeds regioselectively according to NMR spectra. It proceeds at a low temperatureç cooling the reaction mixture with ordinary ice. The main reaction products, diethers -3-bromo (iodine) -1,2-propanediol, are formed in high yields. İt founded that the alkoxyhalogenation of allyl ethers with propinol proceeds regioselectively with fixation of the halogen atom to the peripheral carbon atom of C=C bond. The yields of bromine-containing products are higher than those for iodine analogues. Iodine-containing products boil at a higher temperature than bromine analogues. In the reaction products, substances with the replacement of the halogen atom with unsaturated alcohol are not observed. The reaction was monitored by means of thin layer chromatography. Similar synthesized compounds are used as biologically active compounds.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.