Acetone extracts of the leaves of Anoigeissus leiocarpus collected from two different geographical locations from Nigeria were analysed for their phytochemicals, antioxidants, antibacterial, antimycoplasmal and cytotoxic activities. It was shown that plant from the colder region has higher yield and better activities than that from warmer region; having bacterial minimum inhibitory concentration (MIC) value of 0.08 mg/ml and mycoplasmal MIC value of 0.16mg/ml. The result showed that there were variations between the two plant extracts in their activities such as antimicrobial, phytochemicals, antioxidants and cytotoxicity.
Spigelia anthelmia Linn is used as a herb and is a common annual weed of cultivation in open re-growths, on unused land in towns as well as on road sides. The plant can grow to approximately 30 cm in height. The aim of this study was to screen extracts of Spigelia anthelmia for their anthelmintic activity against an experimental Nippostrongylus braziliensis infection in rats. Acute oral toxicity occurred at a dose of 1,140mg/kg, while anthelmintic trials against Nippostrongylus braziliensis in rats using the aqueous fraction showed a progressive decrease in worm count with increasing dose (10, 13, 16, 20 and 25 mg per kg body weight) (p < 0.05). At 25 mg per kg body weight, the worm count was significantly lower than that at 10mg per kg body weight (p < 0.05).
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