The synthesis of copper nanoparticles (CuNPs) using Wrightia tinctoria (Wt) R.Br extract is defined in this article as being convenient, environmentally friendly, and non-toxic. UV-visible spectrophotometry, FT-IR, XRD, particle size analyser, SEM-EDAX and TEM methods were used to describe the physicochemical properties of Wt extract mediated synthesized CuNPs (Wt-CuNPs). The Wt-CuNPs synthesized was found to be monodispersed and spherical, with an average size of 15 nm. Gas chromatography and mass spectrometry (GC-MS) research revealed that the Wt R.Br plant extract contains various phytochemical compounds. The properties of Wt-CuNPs were verified by the findings of characterization tests. Via in silico molecular docking experiments with established targets, the underlying mechanisms of cytotoxicity against breast cancer and larvicidal behaviour against Aedes aegypti of Wt-CuNPs were investigated. Interestingly, in vitro cytotoxicity studies showed 50% cell death (IC 50 ) of Wt-CuNPs treated MCF-7 cells and Vero Cells (Kidney epithelial cells) were displayed at 119.23 μg.mL À1 and 898.75 μg.mL À1 , respectively. Also, Wt-CuNPs showed least LC 50 and LC 90 values for larvicidal activity against A. aegypti were of 32.10 μg.mL À1 and 21.70 μg.mL À1 , respectively. Furthermore, Wt-CuNPs is found to be less toxic and biocompatible in haemolytic assays. The findings clearly showed that biosynthesized Wt-CuNPs have been used as a possible anticancer and larvicidal agent, as well as being environmentally friendly.
The fabrication of high-yield, reproducible and cost-effective photo-electrocatalyst Bi2O3/NiCo2O4 was investigated by hydrothermal route. It was embedded with reduced graphene oxide (rGO), semiconducting polyaminoanthraquinone (PAAQ), and hydrotalcite (HTs) successfully. Synthesized...
The present study has focused the synthesis of Fe 3 O 4 -ZnO and citric acid/glycine-modified Fe 3 O 4 -ZnO nanocomposites by coprecipitation followed by sol-gel method. The structural elucidation of modified Fe 3 O 4 -ZnO nanocomposites has revealed by XRD, SEM-EDX, FT-IR, and UV-Vis spectrophotometer studies. The analytical studies have revealed that the average crystallite size found to be 10-47 nm with spherical shape on smooth surface. The band gap energy range has found to be 1.52 to 3.12 eV. The catalytic activity of synthesized nanocomposites has undergone the oxidation of benzaldehyde, and the antibacterial activity has done using gram-negative bacteria Escherichia coli. The experimental results have concluded that the citric acid-iron oxide nanocomposite has showed the higher yield in oxidation reaction and the citric acid-iron oxide nanocomposite has showed higher efficiency in antibacterial activity comparatively.
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