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The prevalence of virus warts of the hands among butchers has been determined in three industrial butcheries by examining 536 meat-workers at their places of work. A prevalance of 23-8% has been found, which is significantly higher than the 8-5% prevalance found in 965 control adult subjects examined in different firms where manipulation of food does not occur. Further, the prevalence of virus warts of the hands has been found significantly higher in the 199 workers of one butchery (32-1%) than in 199 control subjects (10-1%) strictly matched for age and sex, and belonging to the same industrial area. In butchers, warts of the dorsal aspects of the hands are statistically less frequent than in control subjects when three localizations are considered (dorsal, palmar, dorsal plus palmar). No significant difference is observed when single localizations (dorsal or palmar) are considered. A definite explanation of the high prevalence of virus warts of the hands among butchers has not been found so far; some hypotheses are discussed in the light of the presnt study.

The measurement of forced expiratory volume (FEV_S) was shown to be a valuable parameter in the study of various bronchodilators in coal-miners suffering from bronchospastic conditions. The study was performed in 124 coal miners. The effects of a new selective betamimetic bronchodilator, Th 1165 a, in the form of a metered aerosol, tablets and ampoules, were compared with those of isoprenaline (Aleudrin), orciprenaline (Alupent), adrenaline (epinephrine) and atropine methyl nitrate. The drugs were compared as to intensity and duration of action, cardiac action being monitored continuously with an E.C.G. The results were statistically evaluated and are presented as tables and graphs. Th 1165 a was shown to be superior to all the betamimetic bronchodilators tested with regard to its selective action on the bronchi, its duration and intensity of action as well as lack of side effects and absence of tolerance following long-term administration.

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