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STUDIES ON THE INTERACTION OF HUMAN IMMUNOGLOBULIN E WITH RAT MAST CELLS L. P e r e l m u t t e r , A . L i a k o p o u l o u and J . A . P h i l l s R e s e a r c h L a b o r a t o r i e s H e a l t h P r o t e c t i o n B r a n c h N a t i o n a l H e a l t h and Welfare O t t a w a , O n t a r i o KM OL2 A b s t r a c t I n t r o d u c t i o n I t h a s b e e n d e m o n s t r a t e d t h a t r a t mast c e l l s u n d e rgo s p e c i f i c m o r p h o l o g i c a l c h a n g e s when i n c u b a t e d f o r s h o r t p e r i o d s of t i m e (3 min) w i t h I g E -t y p e r e a g i n s a n d s p e c i f i c a l l e r g e n o r IgE myeloma p r o t e i n ( N D o r PSI a n d a n t i -h u m a n I g E serum (1-4). or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher. Immunol Invest Downloaded from informahealthcare.com by Stanford University on 11/18/14 For personal use only. Immunol Invest Downloaded from informahealthcare.com by Stanford University on 11/18/14 For personal use only. Immunol Invest Downloaded from informahealthcare.com by Stanford University on 11/18/14 For personal use only.

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