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potential of filling this need because of structures are different from those of the more studied and their those of the more action may too very likely differ. [1] In this growing interest, many of the Phytochemical bioactive compounds from a medicinal plants have shown many pharmacological activities. [2,3] Screening of various bioactive compounds from plants has lead to the discovery of new medicinal drug which have efficient protection and treatment roles in against various diseases. [4] The rapid emergence of multiple drug resistance strains of pathogens to current antimicrobial agents has generated an urgent intensive for new antibiotics from medicinal plants. Many medicinal plants have been screened extensively for their antimicrobial potential worldwide. [5,6] Endophytic fungi are relatively unexplored producers of metabolites useful to pharmaceutical and agricultural industries. [7] Endophytes are the microorganisms that grow inside the plants; both

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A series of new 3-(glycinamido)-benzofuran-2-carboxamide and 3-(b-alanamido)-benzo furan-2-carboxamide derivatives (5a-o) were synthesized for the purpose of developing the new bioactive chemical entities and evaluated for their in vitro antimicrobial, anti-inflammatory and DPPH radical scavenging activities. The synthesized compounds were characterized by NMR, IR, Mass and X-ray crystallographic techniques. ª 2015 Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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