Segmental blood flow, velocity, and vessel diameter were measured in 21 eyes of diabetic individuals with diabetes type 1 and 2. The results for arterial blood flow, velocity, arterial and venous vessel diameter in diabetes show significant differences from the results measured in normal individuals. These flow magnitudes, excluding arterial diameter, significantly depend on the duration time of diabetes. The retinal blood flow magnitudes alter before the marks of diabetic retinopathy are visible. There are differences between the results in diabetes type 1 and type 2 regarding dependence on the duration time of diabetes.
In seven diabetics of type 1 and seven of type 2, the flow physiologic magnitudes were measured in a retinal quadrant before and after photocoagulation. The segmental blood flow, the arterial flow velocity, and the diameters of artery and vein are smaller after photocoagulation than before. Investigations into the time course of the flow-physiologic parameters following photocoagulation show that the flow-physiologic values are stationary about 2 weeks after photocoagulation.
Blood flow, arterial velocity, and vascular diameter were measured in patients with retinal vessel occlusion before and after treatment, especially after light coagulation. The mean values in the patient group showed significantly reduced blood flow and velocity compared to the normal group. The mean group difference before and after therapy revealed that while there is an increase in blood flow after treatment, the normal value is not reached. Individual patient values indicated both increased and decreased blood flow and velocity after treatment as compared with the values before therapy. There are various stages in microcirculatory disease and the microcirculation also behaves differently after treatment, which could be observed by measurement in vivo of the physiological flow parameters.
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