Background and Objectives: Diagnosis of mental disorders and resilience of individuals during the epidemic of diseases is necessary for planning. The purpose of this study was to determine the resilience, stress, depression and anxiety of households in Anar city at the time of the outbreak of COVID-19 disease. Materials and Methods: The present descriptive study was conducted among 453 households in Anar city (from Rafsanjan County). Data were gathered using questionnaires and in a web-based approach. Data were analyzed using independent t-tests, Tukey's post hoc test and Spearman's correlation coefficient. Results: The results showed that 251 (57.7%), 233 (51.4%) and 260 (57.3%) participants had levels of stress, anxiety and depression, respectively. The mean and standard deviation of resilience score was 37.55±19.18. There was a significant relationship between anxiety and level of education, job and age and also depression and job levels. Conclusion: Due to the high prevalence of mental disorders and low resilience during the epidemic of the disease and its consequences, psychological interventions are recommended.
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