Immobilizing (bio-) receptor molecules via 3-(triethoxysilyl)propylsuccinic anhydride makes subsequent binding site blocking dispensable, while maintaining receptor specificity for target analytes.
We present a simple method to microfluidically align and trap 1D nanostructures from suspension at well-defined positions on a receiver substrate for the fabrication of single-nanowire field effect transistors (NW FETs). Our approach allows for subsequent contacting of deposited NWs via standard UV-lithography. We demonstrate that silicon as well as copper(II) oxide NWs can be processed, and that up to 13 out of 32 designated trapping sites are occupied with single-NW FETs.One-dimensional (1D) nanostructures such as nanowires (NWs) can be readily synthesized in a "bottom-up" approach from metals, 1-4 organic molecules 5,6 and semiconductors. 7-28 Compared to "top-down" structures, "bottom-up" 1D nanostructures offer superior electronic properties, 7 better control in the fabrication of heterostructures with axial 1,2,8 and radial 9 variations, and smaller achievable structures down to the molecular scale. 10,11 The great potential of "bottom-up" NWs has been demonstrated in particular in nano-electronics and -photonics, e.g. in † Electronic supplementary information (ESI) available: Detailed description of fabrication of SU-8 2010-based master structures, PDMS-based so lithography, assembly of ow set-up, layout of the channel structure for alignment and trapping of NWs, in silico study of ow behavior, tilt of trapped NWs, NW suspension preparation, mask alignment mark deposition, contacting the NWs, device characterization. Time laps movie of NW trapping procedure. See www.rsc.org/advances 94702 | RSC Adv., 2015, 5, 94702-94706 This journal is
The combination of nanoscaled materials and biological self-assembly is a key step for the development of novel approaches for biotechnology and bionanoelectronic devices. Here we propose a route to merge these two subsystems and report on the formation of highly concentrated aqueous solutions of silanized silicon nanowires wrapped in a lipid bilayer shell. We developed protocols and investigated the dynamics of lipid films on both planar surfaces and silicon nanowires using fluorescence recovery after photobleaching, demonstrating fully intact and fluid bilayers without the presence of a lipid molecule reservoir. Finally, the experimental setup allowed for in situ observation of spontaneous bilayer formation around the nanowire by lipid diffusion from a vesicle to the nanowire. Such aqueous solutions of lipid coated nanowires are a versatile tool for characterization purposes and are relevant for newly emerging bioinspired electronics and nanosensorics.
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