This report describes clinical and pathological findings associated with closantel (a halogenated salicylanilide anthelmintic) overdosage in a 3-year-old goat. The clinical signs included blindness, incoordination, ataxia, depression of the palpebral and pupillary reflexes, and recumbency. No gross lesions were noted in tissue or organs at necropsy, but microscopic lesions were seen in nervous tissue and hepatic cells. Polioencephalomalacia was clearly evident. Bilaterally symmetrical status spongiosus of the white matter of the brain, bilateral laminar necrosis, microcavitations, ischaemic cell change and severe degeneration of the cerebellum were seen in nervous tissue. Fatty change and hydropic degeneration in the liver and hepato-cellular degeneration were observed histologically

Evaluation of the effectiveness of sodium hyaluronate, sesame oil, honey, and silver nanoparticles in preventing postoperative surgical adhesion formation. An experimental study 1 AbstractPurpose: To evaluate the effectiveness of sodium hyaluronate, sesame oil, honey, and silver nanoparticles in preventing of postoperative surgical adhesion formation. Methods: Forty male Wistar rats were randomly assigned into five groups with eight rats in each group including control, hyaluronate, sesame, honey and silver groups. After two weeks the animals underwent laparotomy and were evaluated by two different blinded surgeons for severity of adhesions based on the two different classification scoring systems including Nair classification and cumulative adhesion scoring scale. Results:The scores of severity of adhesions in the hyaluronate and sesame groups were significantly lower than the control group based on the Nair classification (both P-values = 0.02), however based on the cumulative adhesion scoring scale just the score of severity of adhesions in the hyaluronate group was significantly lower than the control group (P-value = 0.02). In the hyaluronate group the severity of adhesions was decreased by 48% based on the cumulative adhesion scoring scale. Conclusions: Sodium hyaluronate and sesame oil may have a significant effect in preventing postoperative surgical adhesion formation.

Necrolytic migratory erythma (NME) as a rare skin disorder that can affected Perineum, distal extremities, lower abdomen and face are the most commonly affected sites.It can be as a part of Glucagonoma syndrome that is defined as an association of glucagonoma with NME, hyperglucagonemia, glucose intolerance, anemia and weight loss. Here, Authors describe a woman admitted to the dermatology ward with NME which was later found to be associated with glucagonoma and multiple hepatic lesions.

A 3-years-old Iranian cross-breed ram with history of repeated local sweating, severe pruritus of body surface was referred to the veterinary clinic. On clinical examination wetness, warmness, pruritus and thickness of affected area were observed. In affected area, hair coat was staring and draggy. Body temperature, heart and respiratory rates were 40.4 degrees C, 120 beat min(-1) and 40 min(-1), respectively. Hematologic indices including packed cell volume, total and differential white blood cell (WBC) and total red blood cell (RBC) were normal. Laboratory examinations of skin scrapings confirmed infestation with Psoroptes ovis. Histopathologic findings included dilation of sweat glands, hyperplasia of sebaceous glands, hyperkeratosis, ulcer and scab formation and eosinophilic dermatitis. History and clinical findings association with the skin scraping and histopathologic findings indicated localized seborrhoeic dermatitis with hyperhidrosis. After treatment with ivermectin at the dose rate of 0.2 mg kg(-1), all clinical signs subsided. This confirmed that the cause of seborrhic dermatitis and hyperhidrosis was mite infestation and other possible causes were ruled out. So this is the first report of localized seborrhoeic dermatitis with hyperhidrosis due to mite infestation in animals.