The aim of this study was to examine the influence of static, inhomogeneous magnetic fields on prostaglandin synthesis in L-929 and 3T3 mouse fibroblasts. Two pairs of magnets, one CoSm and the other NdFeB, were attached 10 mm apart under the culture chamber. One pair was in the attracting position and the other in the repelling position. The maximum magnetic induction measured was 85 respectively 120 mT and the incubation time was 72 hours. Control groups consisted of untreated cells and cells under the influence of demagnetized magnets. The following measurements were taken: prostaglandin synthesis (PGE2), protein content (GP), and the number (Z) of cells (only L-929 mouse fibroblasts). The data were analyzed statistically using the Tukey test and the significance niveau was set at alpha = 0.05. The results using this method demonstrated that the measurable effects of in vitro treatment of mouse fibroblasts with static magnetic fields of varying induction did not significantly differ from the control groups. The sensitivity of our method was verified beforehand with a recombinant, human TNF alpha stimulated reference group.
Until recently, surgical correction of the jaws has been widely regarded as the most effective treatment of open bites in the permanent dentition. In the following case report an open bite was treated non-surgical by intrusion of the molars with a magnet appliance. The forces of repelling magnets, fixed opposite in the upper and lower jaw were used to intrude the first and second molars. This intrusion allowed an autorotation of the mandible upward and forward to close the open bite. By reduction of the open bite of about 3 mm a surgical intervention could be avoided.
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