A combination of pioglitazone, Peg-IFN-alpha-2b and ribavirin increased RVR, SVR and decreased IR, compared with patients given Peg-IFN plus ribavirin without an increase in adverse events.
pandemic has forced us to provide day case LAT with IPC placement without pleurodesis to minise transmission risk. We thus describe our local experience. LAT is performed in theatre under conscious sedation. Methods: All the notes of patients requiring day case LAT between July 2020-Dec 2020 were analysed. Basic demographics were collected as well as diagnoses and what interventions were performed. A descriptive analysis of the data was performed. Results: 13 patients underwent day case LAT. All had negative preoperative Covid-19 swabs. Mean age was 69.7 years (range 24-82). 10 were male and 3 female. Definite diagnoses included 5 lung cancers, 4 mesotheliomas and 2 fibrinous pleuritis. The lung did not deflate, not allowing for biopsies in 2 patients. Non-malignant diagnoses are currently presumed. 10 IPCs and 1 large bore drain were inserted due to 1 immedidate complication (surgical emphysema). 1 patient developed an empyema within 30days. 8 out of the 10 IPCs have already been removed due to pleurodesis occuring (mean number of days 27.5, range 16-72). All patients were discharged on the same day except 1 patient who required a large bore drain and stayed overnight. Conclusions: We have thus transformed our service after more than a decade of providing LAT as an inpatient service. This is a small cohort of patients but proves the feasibility and safety of day case LAT with massive reduction in inpatient stay. The Covid-19 pandemic has transformed our service but for the better. Further qualitative work should elucidate the acceptability of such a pathway for patients. Legal entity responsible for the study: The authors. Funding: Has not received any funding. Disclosure: All authors have declared no conflicts of interest.
or PTFE-graft (n=1) in total vascular occlusion (mean of 29.6 min.). Severe morbidity defined as Dindo Clavien >3a was found in 3 patients; one patient died due to small-forsize syndrome. Mean length of stay at ICU and hospital were 9.0 and 34.3 days, respectively. R0-resection was achieved in 5 cases (twice a R1-situation). Disease-free survival was 24.6 months with an overall survival of 34.4 months. Conclusion: Ante situm liver resection offers the opportunity to achieve surgical cure in otherwise unresectable tumors. Nevertheless, this approach remains challenging with need for complex vascular reconstruction.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.