Fistula in ano could be treated effectively with Ksharasutra, the surgical linen impregnated with special Ayurvedic medicine of alkaline in nature. There are different theories in existence claiming the mode of action of the thread in fistula in ano. Antibacterial activity of the Ksharasutra thread is one of it. Aim of this study is to identify the antibacterial activity of the Ksharasutra. Main objective is to determine the antibacterial activity by using Antibacterial Sensitive Test (ABST). The (ABST) test bacteria were Staphylococcus aureus, Streptococcus pyogens, Escherichia coli, and Pseudomonas aeuruginosa, isolated from fistula specimens (Clinical cultures), and the standard strains. The Ksharasutra extract (100 mg/ml) was aseptically introduced into respective agar wells. Amoxicillin (100 mg/ml) was used as the positive control and the kept 50 µl distilled water was for the negative controls. Inhibition zones of ≥7 mm diameters around the well were regarded as significant susceptibility of the organisms to the extract. One way anova used as statistical method to analysis the data. Higher Zone of inhibition was observed in the ksharasutra thread extract for Staphylococcus aureus, 33.33±0. Escherichia coli, 30.60±0.33, Streptococcus pyogen 24.005±0.57 and Pseudomonas.. aeruginosa, 9.66±0.33. Standard antibiotic possess relatively low Zone of inhibition compare to the ksharasutra thread extract. Antibacterial activity of Ksharasutra due to the presence of curcumin and some of the inorganic compounds in kshara Cu, Zn Ca etc. So the Ksharasutra possess significant (P<0.05) Antibacterial activity in contrast to the standard antibiotic.
The Ksharasutra procedure is an effective non-surgical treatment for the fistula in ano. The operative technique are uncertain and the recurrence rate is (11to 44) % 1, 2. Apart from this, the operative management has some adverse effect like incontinence of feces, loss of gluteal cushion and postoperative stenosis. The treatment of Fistula in ano by Ksharasutra is very simple, easy and safe with least recurrences. It is one
In spite of the advances that have been made, the management of chronic wounds is still a challenge for the physician. In the present study, an attempt was made to develop simple and effective treatment for the management of chronic wounds that are not responding to conventional treatment modalities by using Thila lepa as an external wound application. Present study was conducted to evaluate the effect of selected herbal place Thila lepa in the management of chronic wound. Randomly selected 60 cases of chronic wound were assigned in to two groups. The test group was treated with the selected herbal paste. While the control group being treated with Rogane Kaash Cream. The effects of the treatment were evaluated on the basis of wound area, amount of discharge, oedema, itching, pain and tensile strength of wound. In this study among 30 cases 24 (80%) cases have got the wound completely healed. The result of the present study reveals that the application of Thila lepa successful external application consisting of wound healing properties in the management of chronic wound.
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