Fistula in ano could be treated effectively with Ksharasutra, the surgical linen impregnated with special Ayurvedic medicine of alkaline in nature. There are different theories in existence claiming the mode of action of the thread in fistula in ano. Antibacterial activity of the Ksharasutra thread is one of it. Aim of this study is to identify the antibacterial activity of the Ksharasutra. Main objective is to determine the antibacterial activity by using Antibacterial Sensitive Test (ABST). The (ABST) test bacteria were Staphylococcus aureus, Streptococcus pyogens, Escherichia coli, and Pseudomonas aeuruginosa, isolated from fistula specimens (Clinical cultures), and the standard strains. The Ksharasutra extract (100 mg/ml) was aseptically introduced into respective agar wells. Amoxicillin (100 mg/ml) was used as the positive control and the kept 50 µl distilled water was for the negative controls. Inhibition zones of ≥7 mm diameters around the well were regarded as significant susceptibility of the organisms to the extract. One way anova used as statistical method to analysis the data. Higher Zone of inhibition was observed in the ksharasutra thread extract for Staphylococcus aureus, 33.33±0. Escherichia coli, 30.60±0.33, Streptococcus pyogen 24.005±0.57 and Pseudomonas.. aeruginosa, 9.66±0.33. Standard antibiotic possess relatively low Zone of inhibition compare to the ksharasutra thread extract. Antibacterial activity of Ksharasutra due to the presence of curcumin and some of the inorganic compounds in kshara Cu, Zn Ca etc. So the Ksharasutra possess significant (P<0.05) Antibacterial activity in contrast to the standard antibiotic.
The Ksharasutra procedure is an effective non-surgical treatment for the fistula in ano. The operative technique are uncertain and the recurrence rate is (11to 44) % 1, 2. Apart from this, the operative management has some adverse effect like incontinence of feces, loss of gluteal cushion and postoperative stenosis. The treatment of Fistula in ano by Ksharasutra is very simple, easy and safe with least recurrences. It is one
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.