To address the issue of global warming, there is a trend towards low-carbon economies in world economic development. China’s rapid economic growth and high carbon energy structure contribute to its large carbon emissions. To achieve sustainable development, China must transform its industrial structure to conserve energy, reduce emissions, and adapt to climate change. This study measured the carbon entropy and carbon emission efficiency of 25 industries in the Beijing-Tianjin-Hebei region from 2000 to 2015 by building carbon entropy models and total factor industrial carbon emission efficiency evaluation models. The study showed that: (a) Priority development industries in the Beijing-Tianjin-Hebei region were expanding, the regional competitiveness of the moderate development industry was improving, and the proportion of restricted development industries had dropped significantly; (b) the spatial distribution of the three types of industries presented a pattern of concentric rings, with priority industries at the core, surrounded by moderate, then by restricted development industries; (c) the status of medium- and high-efficiency industries had improved, while the status of low-efficiency industries had decreased. Spatially, high- and low-efficiency industries were becoming concentrated, and medium-efficiency industries were becoming dispersed; (d) considering carbon entropy and carbon emission efficiency, the path of industrial structure transformation and upgrading and layout optimization in Beijing-Tianjin-Hebei region was proposed.