Сarcinogenic substances in the atmospheric air of Dnipro city and risk to the population

Сердюк, А.М.; Chernychenko, I. O.; Lytvychenko, O. M.; Бабій, В.Ф.; Kondratenko, O.Ye.; Hlavachek, D.O.

doi:10.26641/2307-0404.2021.1.228020

Cited by 2 publications

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References 4 publications

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“…Найбільш небезпечними у цьому відношенні є нітрозаміни та хром VI, індивідуальний ризик впливу яких визначався як насторожувальний, тоді як канцерогенний ризик інших речовин -у межах допустимого. Проте, зважаючи, що канцерогени у переважній більшості є речовинами односпрямованої дії за впливом на окремі критичні органи та системи, більш об'єктивним критерієм є показник сумарного ризику, який визначався нами у місті Дніпро у 2015-2020 рокіах у межах 2,5-3,9 випадків раку на 1000 населення, або 2,5-3,9х10 -3 , що свідчить про високу небезпеку забруднення атмосферного повітря для населення [11].…”

Section: Conclusion: тHe Real Air Pollution In Populated Areas Poses ...unclassified

Chemical carcinogens in the environment of ukraine: risk to the population, ways of prevention, improvement of hygienic regulation

Chernychenko,

Balenko,

Lytvychenko

et al. 2023

Dovkil Zdor

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The purpose of this work was to determine the carcinogen-hazardous factors in the environment and the criteria for assessing their danger to the population in modern conditions (pre-war period). Materials and methods of research: reports of research works of the Laboratory of Hygiene of Carcinogenic Factors and Nanomaterials of the SI «O.M. Marzieiev Institute for Public Health, NAMS of Ukraine» and own publications over the past 5 years. Bibliosemantic, analytical, hygienic and medical-statistical methods were used to process the materials. Results. The analysis of field and analytical studies has shown that over the past 20-25 years old, against the backdrop of a reduction in industrial emissions, the volume of use of plant protection products and plant products in agricultural activity has increased significantly, and in everyday life – household chemicals, cosmetics, etc., most of which contain specific substances – endocrine disruptors. It was shown that over the years, the rate of increase in the rate of cancer of the endocrine organs (cancer of the mammary, thyroid, prostate glands), uterine body and ovaries increases. The obtained data indicate a trend towards rejuvenation of oncological diseases of hormone-dependent organs. The danger of atmospheric air pollution in cities has been studied; a comparative assessment of carcinogenic and non-carcinogenic risk for the population in a highly industrialized city with a complex of ferrous metallurgy enterprises and a city where there are no specific sources of pollution was carried out. It was concluded that for study of environmental issues regarding the state of the air environment, it is sufficient to use hygienic indicators - maximum permissible concentrations and total pollution indicators, while for the assessment of the impact on human health, the use of risk indicators is more adequate. This raises the question of the compliance of domestic hygienic (medical and sanitary) regulations with international risk indicators. This is especially true for factors with mutagenic and carcinogenic properties. The analysis of risk indicators for a number of carcinogenic substances included in the domestic regulatory and methodological bases at the level of their maximum permissible concentrations proved that the standards for atmospheric air according to the international classification scale correspond to an acceptable risk (1 - 104) for only 26% of substances, and for air of the working area - 45% of substances. Consequently, most of the hygienic standards, both in the atmospheric air of populated areas and in the air of the working area, according to international standards, do not meet the safety requirements for the population and need to be revised using international approaches and focusing on the risk criteria for the development of neoplasms due to the action of individual compounds. Conclusions: the real air pollution in populated areas poses a certain danger to the population and requires preventive measures to reduce it. The currently existing national regulatory framework for the permissible content of carcinogenic substances in the air environment (atmospheric air and air of the working area) does not meet the requirements of the EU and the USA.

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Section: Conclusion: тHe Real Air Pollution In Populated Areas Poses ...unclassified

Chemical carcinogens in the environment of ukraine: risk to the population, ways of prevention, improvement of hygienic regulation

Chernychenko,

Balenko,

Lytvychenko

et al. 2023

Dovkil Zdor

Self Cite

View full text Add to dashboard Cite

show abstract

Analysis of the regulatory and methodological base of EU COUNTRIES and USA for determining the hygienic standards of carcinogenic substances for the working area (review of the literature and regulatory documents)

Chernychenko,

Balenko,

Lytvychenko

et al. 2024

Dovkil Zdor

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The aim of the work was to analyze the current state of determining the regulations of chemical substances, including carcinogens, for the conditions of occupational influence prevention. Research materials and methods: sources of scientific literature, EU directives, materials of the European Air Protection Agency. Methods of empirical and theoretical analysis of scientific information was used. The results. It was shown that international experience in regulating harmful factors in the air of the working area is extremely important for extrapolating their data to the conditions of Ukraine, for which the problem of work environmental pollution is extremely important, especially in view of the probable impact on oncopathological processes among workers. This is due to the fact that the majority of active domestic enterprises of various industries are considered according to the classification of the International Agency for the Study of Cancer as directly carcinogenic to humans. The data are presented, which indicate the constant growth of oncological diseases both among the population as a whole and among working contingents. The work analyzes organizational and methodical approaches to the development of measures to prevent the impact of harmful factors on workers. It has been proven that the main purpose of the regulations of the European Agency for Chemical Compounds is aimed at ensuring a high level of protection of the population and the environment from the harmful effects of chemicals and at promoting the functioning of the internal market through the support of innovative technologies and increasing competitiveness. To solve these issues, a number of declaratory regulations have been developed in the EU countries, which are illustrated by the List of carcinogenic factors and established occupational exposure limits. It has been established that the most effective form of protection for workers is the hygienic regulation of chemical compounds. According to the EU Directives, two types of limits are established: an indicative occupational exposure limit and a limit based on the assumption of a certain risk. Today, limits on the level of concentrations corresponding to the risk of exceeding the risk of developing cancer during life at the level of one case per 10,000 (х10-4) workers are recommended for EU countries. This approach determines the presence of regulations in the EU countries at a lower level compared to domestic hygiene standards. A conclusion is made regarding the need to review the domestic regulatory framework and harmonize it in accordance with EU requirements.

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Сarcinogenic substances in the atmospheric air of Dnipro city and risk to the population

Cited by 2 publications

References 4 publications

Chemical carcinogens in the environment of ukraine: risk to the population, ways of prevention, improvement of hygienic regulation

Chemical carcinogens in the environment of ukraine: risk to the population, ways of prevention, improvement of hygienic regulation

Analysis of the regulatory and methodological base of EU COUNTRIES and USA for determining the hygienic standards of carcinogenic substances for the working area (review of the literature and regulatory documents)

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