Епідемічні Спалахи Та Епізоотії Туляремії Як Наслідок Авіаційних Бомбардувань У Косові

Rusev, I.; Zakusilo, V. N.

doi:10.15421/021235

VDNUBM

2012

DOI: 10.15421/021235

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Епідемічні Спалахи Та Епізоотії Туляремії Як Наслідок Авіаційних Бомбардувань У Косові

I. Rusev¹,

V. N. Zakusilo²

Abstract: Analysis of mass outbreak of tularaemia in humans of Kosovo after the mass bombardments of the territory in 1999 suggests the possible anthropogenic nature of its origin. The emergence of mass epizooty among wild mammals and mass outbreaks of the disease among people of that dangerous infection may be possible in the case of activation of natural foci, or as a result of the infection import. Natural foci of tularaemia in Kosovo were not registered earlier. Consequently, outbreaks and epizootics of tularaemia m… Show more

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Cited by 5 publications

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Generalized form of tularemia in pediatric surgeon practice: Difficulties of diagnosis and treatment

Никитин

Гусева

Goldenberg³

et al. 2023

Ross. vestn. perinatol. pediatr.

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Tularemia in the practice of a pediatric surgeon is a rare disease, and abdominal and generalized forms of it are not detected without specific laboratory diagnostics. The long-term serious condition of patients, intoxication, abdominal pain with excluded acute surgical pathology in children force differential diagnosis with rare infectious diseases, including tularemia. In the Russian Federation, up to 30 children a year are diagnosed with tularemia, with the exception of outbreaks of the disease in some years. At the same time, the generalized form is detected in no more than 10% of patients. The authors presented a clinical case of a generalized form of tularemia in a 17-year-old patient. The disease started with abdominal pain, diarrhea and vomiting. At the beginning of the disease, a diagnostic error was made — suspicion of ovarian inversion and laparotomy according to Pfannenstiel. In the further development of the disease, pronounced ascites were detected with the production of up to 5 liters of effusion per day, damage to the kidneys, liver, heart, gastrointestinal tract. Laboratory data revealed leukocytosis up to 89×109, accelerated erythrocyte sedimentation rate, increased levels of creatinine, urea, transaminases, C-reactive protein, proteinuria persisted for a long time. Indirect hemagglutination reaction with tularemia diagnosticum made it possible to establish the diagnosis of tularemia, generalized form. During two weeks of the disease, an 8-fold increase in the titer of antibodies was noted. Syndrome therapy and specific antibacterial therapy made it possible to stop the infectious process and discharge the patient home on the 44th day of the illness with recovery.

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Generalized form of tularemia in pediatric surgeon practice: Difficulties of diagnosis and treatment

Никитин

Гусева

Goldenberg³

et al. 2023

Ross. vestn. perinatol. pediatr.

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Episootological features of tularemia in the Donetsk region

Skripka

2024

Med. vestn. Ûga Ross.

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Objective: to evaluate epizootic monitoring of tularemia in the Donetsk region.Materials and methods: methods of retrospective, statistical, and comparative analysis were used. The sources of infection were investigated using serological and biological methods. The data of industry statistical reporting on form No. 40-annual of the department of especially dangerous infections of the Donetsk regional Sanitary and Epidemiological Station (since 2013 — SSESU, since 2015 — Republican Center for Sanitary and Epidemiological Surveillance of the State Sanitary and Epidemiological Service of the Ministry of Health of the DPR) were used. 20 "Maps of epizootological and epidemiological examination of the focus of zoonotic disease" (F.391/y) were studied.Results: since 1987, the number of enzootic territories in the Donetsk region has increased annually: from 2 settlements in 1987 to 79 (in 4 cities and 16 districts) in 2023. With the beginning of active hostilities, the epidemic process of tularemia in Donbass has sharply intensified. Antibody titers (1:80 and 1:160) for tularemia were detected in environmental samples: in the North Steppe zone — 6.2%, Donetsk-Kryazhnaya — 10.4%, Primorsko-steppe — 15.8%. In the study of mouse-like rodents, 6 cultures of Francisella tularensis holarctica biovar II era R were isolated, resistance of the strain to ampicillin, cefotaxime, erythromycin, clindamycin, polymyxin was established; sensitivity to gentamicin, fluoroquinolones, rifampicin, doxycycline, levomycetin.Conclusions: the activation of epizootic processes of tularemia in the DPR is associated with the conduct of hostilities. High titers of antibodies to tularemia in environmental samples are noted in the south of the Donetsk region.

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Tularemia as a cause of lymphadenopathy in adults and children

Утенкова

Oparina

Малкова

2019

test

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Objective: to study the clinical and epidemiological features of tularemia to identify its differences from other diseases. flowing with lymphadenopathy. Materials and methods The study included patients living in the Kirov region undergoing tularemia from 2012 to 2018. For the laboratory confirmation of the diagnosis of tularemia used agglutination with tularemia antigen and a method of solid phase ELISA. The results Among the patients were dominated by citizens (63.4%). All cases were recorded in the summer. Infection usually occurred during the bites of flying insects. The most common manifestations of the disease were fever and lymphadenitis. Among the clinical forms prevailed ulcero – glandular (71,7%). The correct diagnosis at the prehospital stage is exhibited only in 28.6% of patients. Conclusion Tularemia remains an actual natural focal infection. To reduce the incidence of disease, it is necessary to increase the volume of vaccination of the population and regularly improve the knowledge of physicians with regard to endemic infections in the region.

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Епідемічні Спалахи Та Епізоотії Туляремії Як Наслідок Авіаційних Бомбардувань У Косові

Cited by 5 publications

References 7 publications

Generalized form of tularemia in pediatric surgeon practice: Difficulties of diagnosis and treatment

Generalized form of tularemia in pediatric surgeon practice: Difficulties of diagnosis and treatment

Episootological features of tularemia in the Donetsk region

Tularemia as a cause of lymphadenopathy in adults and children

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