Вплив Ферровету 7,5 % І Фероселу Т На Концентрацію Мінеральних Речовин В Сироватці Крові Поросят, Хворих На Ферумдефіцитну Анемію

Abstract

In the article presents the results of experimental studies on the pharmacological action of iron dextran preparations – ferrovet–7.5%, which in 1 ml dextran containing 75 mg of ferric iron, and ferosel–T, 1 ml of which, in addition to 75 mg of ferric iron, additionally contains 0.3 mg selenium (in the form of sodium selenite) the concentration of minerals in the blood serum of pigs for latent iron deficit anemia.Established that at 21 days postnatal period, in the whey of blood of piglings for latent iron deficit anemia, a level of Calcium was on 11.8%, and to Phosphorus – on to 8.4% lower. Reserves of iron in the indicated period of depot were fully used for hematopoietic and receipt of its mother's milk insufficient for optimal erytrotsytopoez because the concentration of iron in the blood serum of pigs did not satisfy his need for hematopoiesis.In the case of iron dextran preparations for the treatment of iron deficiency anemia pigs found an increase in Calcium, Phosphorus, Selenium and Iron. So on 21 days after birth for piglings, which entered ferrovet 7.5%, in the whey of blood the concentration of Calcium was increased on 30.0% (r < 0.01), to Phosphorus – on 15.6%, and which ferosel–T was entered accordingly increased on 33.4% (r < 0.01) and 19.3%.The concentration of Selenium and Iron in the blood serum of piglets research groups, which used ferrovet 7.5% and ferosel–T is likely to have increased since 7 day experiment. Shown that iron deficit anemia of piglings efficiency of application of preparation of ferosel–T with a medical and prophylactic purpose is higher, than to preparation of ferrovet–7.5 %, that predefined by the combined action of Iron and Selenium.

The influece of different microclimate conditions on productive indices and safety of pigs

“…Вплив факторів мікроклімату і здатність організму адаптуватися до цих умов визначається інтенсивністю біохімічних процесів (Jacelaetal, 2010;Todoriuk, Gutyj, Khomyk, & Vasiv, 2016;Zhu, Wang, Dong, Peng, & Gong, 2016 У наших дослідженнях активність АЛТ в кінці 60-денного віку була вищою ніж у контролі на 5,1%, а АСТ-на 7,11%, ніж у дослідній.…”

Influence of the supplement «Press-Acid» on protein-mineral metabolism and resistance of piglets

“…Проблема профілактики та лікування шлунковокишкових хвороб молодняку, особливо поросят, завжди гостро стоїть перед ветеринарією (Plyashchenko and Sidorov, 1979;Andreyeva, 2010;Todoriuk et al, 2016;Goncharuk, 2016). Отримання та збереження здорового молодняку розглядається у даний час як комплексна проблема, в якій має значення не тільки навколишнє середовище та збудник, а й важлива роль відводиться імунній реактивності організму новонародженого (Furduy, 1979;Solyanik and Solyanik, 2009;Stojanovskyj et al, 2016).…”

Preclinical research of the experimental preparation “Ferosel T”

“…According to reports in the literature, with the intensive introduction of pigs on an industrial basis, in the absence of timely prophylactic measures, the disease of newborn piglets to ferrum-deficient anemia is 100%, and death reaches 35% (Zimmermann, 1995;Lee and Downing, 1979;Rytych et al, 2012;Ohorodnyk, 2013;Berezovskyi et al, 2013;Starzyński et al, 2013;Danchuk et al, 2013;Pu et al, 2015;Hunchak et al, 2018). In order to conduct the treatment and prevention of ferrum deficiency anemia of piglets, we have proposed a new ferro dextran drug "Ferosel T" (ferrocellus T) -an analogue of the officinal preparation "Ferrovet 7.5%", from which the ferrocellus-T is different in the presence of sodium selenite in it (Todoriuk et al, 2016).…”

“…For the treatment and prevention of ferrum deficiency anemia of piglets, we proposed a new saline ferro dextran drug "Ferosel T" -an analogue of the officinal preparation "Ferrovet 7.5%", from which the ferrocellus T is different by the presence of sodium selenite (Todoriuk et al, 2016).…”