α‐Tocopherol and serum lipoproteins

Sundaram, G. S.; London, Robert S.; Manimekalai, S.; Nair, Padmanabhan P.; Goldstein, Phillip J.

doi:10.1007/bf02535020

Cited by 26 publications

(8 citation statements)

References 17 publications

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“…Although more work has been published on the gonadotropins, LH and FSH, the evidence for any abnormality is equivocal. Urinary LH has been claimed to be either low [114] or normal [130] whilst serum LH has been found to be either high [68,185] or normal [90,113]. Most authors have reported normal urinary and serum FSH [90,114], although Mirabile et al [130] claimed that urinary FSH was low during the follicular and high in the luteal phase of the menstrual cycle.…”

Section: (D) Lh Fsh and Tshmentioning

confidence: 95%

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Epidemiology and endocrinology of benign breast disease

Wang

Fentiman

1985

Breast Cancer Res Tr

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Section: (D) Lh Fsh and Tshmentioning

confidence: 95%

“…No difference and no change after vitamin E treatment No significant difference in mean but some higher (>20ng/ml) levels in patients Bahu et al 1980 [10] Bischoff et al 1980 [14] Latteri et al 1980 [103] Tarquini et al i980 [188] Sundaram et al 1981 [185] Simkin 1982 [179] * BBD -benign breast disease.…”

Section: (C) Androgensmentioning

confidence: 98%

Epidemiology and endocrinology of benign breast disease

Wang

Fentiman

1985

Breast Cancer Res Tr

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“…Vitamin E is transported by the plasma lipoproteins [3,50]. Several studies reported that vitamin E increased cholesterol levels in the HDL [3,50]. Other studies reported that vitamin E had little effect on plasma lipoproteins [4,51], and still other studies reported that vitamin E increased cholesterol levels in the VLDL and LDL [5,28].…”

Section: Resultsmentioning

confidence: 92%

“…However, vitamin E, unlike free cholesterol, is found in the lipid core of plasma lipoproteins [49]. Vitamin E is transported by the plasma lipoproteins [3,50]. Several studies reported that vitamin E increased cholesterol levels in the HDL [3,50].…”

Section: Resultsmentioning

confidence: 99%

Does Dietary vitamin E or C Decrease Egg Yolk Cholesterol?

Mohiti-Asli

Zaghari

2010

Biol Trace Elem Res

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An experiment was conducted to determine the effect of dietary vitamin E and C on serum metabolites, yolk cholesterol, egg quality, and performance of layer hens. One hundred sixty-eight commercial Hy-Line W-36 layer hens were randomly divided into seven groups and six replicates with four hens in each. Dietary treatments were introduced after the pre-experimental period (10 days) to adjust egg production. Treatments were levels of vitamin E or C (100, 200, and 400 mg/kg diet) supplementation to the basal diet for 4 weeks, whereas the control group received no supplementation. Egg production, egg weight, and feed consumption were recorded during the study. Shell thickness, Haugh unit score, yolk color, yolk weight, yolk cholesterol, and blood parameters were measured at the end of experiment. There was no significant effect of dietary vitamin E or C on hen performance. Egg yolk cholesterol concentrations decreased linearly by antioxidant vitamin supplementation (P < 0.01). Egg yolk cholesterol reduction did not have any negative effect on egg production rate. Antioxidants, especially vitamin C, increased serum glucose concentration (P < 0.05). Serum total cholesterol content did not change by vitamin supplementation but cholesterol in high-density lipoprotein (HDL-C) decreased and cholesterol in low-density lipoprotein (LDL-C) increased (P < 0.05), as dietary vitamin E or C supplementation increased in diets. These results are in conflict with the previous hypothesis that antioxidants have a role in LDL-C removal from the blood or increasing HDL-C. Vitamin E was more effective than vitamin C in this case and if these results are confirmed by further studies, they may result to revision in researchers' point of view about antioxidant especially in human medicine.

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“…In particular, the change in endogenous sterol excretion appeared to depend mainly on the magni tude of change in serum cholesterol, and not on the type of fat used. It has been suggested that the higher content of tocopherols and ubiquinones in germ oils may lower serum cholesterol in addition to the effect of the fatty acids [12,13,30,31], It is conceivable that these compounds could enhance the ac tion of polyunsaturated fatty acids in the body by protecting them against oxidation [32].…”

Section: Discussionmentioning

confidence: 99%

Metabolic Changes in Healthy Men Using Fat-Modified Diets

Kohlmeier¹,

Riesen²,

Schlierf³

1988

Ann Nutr Metab

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The effect of typical fat-modified diets on serum lipids, lipoproteins and apolipoproteins, on the intravenous fat-tolerance test and on fecal sterol excretion were observed in a group of men living at home and compared to that of their normal diets. Two 4-week-long diet periods alternated with four periods of 6 weeks’ duration during which the men followed their normal dietary habits and accustomed life-styles. According to a randomized cross-over design sunflower oil and corn oil were used as the main fat sources for the fat-modified diets. Both diets lowered total cholesterol considerably acting mainly on LDL cholesterol, without affecting plasma triglycerides significantly. Apolipoprotein A-I and A-II concentrations in serum remained constant, and clearance of triglyceride-rich lipoproteins, as measured by an intravenous fat-tolerance test (Intralipid test), was not significantly affected. While changes of all measured parameters pointed in the same direction, serum total and LDL cholesterol levels were significantly lower with corn oil than with the sunflower oil. Excretion of endogenous sterols (fecal sterol balance) was higher with the fat-modified than with the normal diet. This increase in sterol excretion closely corresponded to the extent of serum cholesterol lowering.

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α‐Tocopherol and serum lipoproteins

Cited by 26 publications

References 17 publications

Epidemiology and endocrinology of benign breast disease

Epidemiology and endocrinology of benign breast disease

Does Dietary vitamin E or C Decrease Egg Yolk Cholesterol?

Metabolic Changes in Healthy Men Using Fat-Modified Diets

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