2012
DOI: 10.1007/s10008-012-1648-0
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α-MoO3 nanowire-based amperometric biosensor for l-lactate detection

Abstract: Large-scale orthorhombic single-crystalline molybdenum trioxide nanowires were synthesized using a facile one-pot hydrothermal method. Lactate oxidase enzyme was immobilized on the nanowires to produce a highly sensitive electrochemical biosensor for L-lactate detection. At an applied potential of 0.5 V, the sensor exhibited a high sensitivity of 0.87 μA/mM with a fast response to L-lactate (90% of response times within 10 s). A linear response was obtained over a concentration range from 0.5 to 8 mM with a de… Show more

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Cited by 16 publications
(2 citation statements)
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“…Other low-dimensional MoO 3 nanostructures have also been applied in sensing of enzymes, such as L -lactate. Shakir et al [189] utilized 1D MoO 3 nanowires to fabricate highly sensitive electrochemical sensors for determining L -lactate concentrations. In this case, lactate oxidase (LO x ) was immobilized on MoO 3 nanowires for the L -lactate sensing at the detection limit of 0.15 mM.…”
Section: Optical Based Biosensorsmentioning
confidence: 99%
“…Other low-dimensional MoO 3 nanostructures have also been applied in sensing of enzymes, such as L -lactate. Shakir et al [189] utilized 1D MoO 3 nanowires to fabricate highly sensitive electrochemical sensors for determining L -lactate concentrations. In this case, lactate oxidase (LO x ) was immobilized on MoO 3 nanowires for the L -lactate sensing at the detection limit of 0.15 mM.…”
Section: Optical Based Biosensorsmentioning
confidence: 99%
“…In another report [10], lactate was detected in the UV range by derivatization with a-bromoacetophenone. Biosensors are the other choice for lactate assays [11][12][13], which are also mostly based on LDH or lactate oxidase (LOD). For instance, an electrochemiluminescencebased disposable biosensor was characterized recently [14].…”
mentioning
confidence: 99%