α-Adrenoceptor-mediated pressor responses in pithed rats fed diets with different calcium contents

Civantos, Beatriz; López‐Miranda, Visitación; Ortega, Ana; Artiñano, Marı́a Amaya Aleixandre de

doi:10.1016/s0014-2999(99)00556-7

Cited by 10 publications

(3 citation statements)

References 42 publications

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“…Several researchers, including our group, have described that before arterial blood pressure stabilizes in SHR, there is an initial period in the life of these animals in which this variable clearly increases (Sánchez et al, 1986;Cabassi et al, 1997;Ló pez-Miranda et al, 1998;Civantos et al, 1999). An initial gradual increase in SBP and DBP was observed in this study in the SHR of control groups, but the intake of captopril, and also the intake of HEW, attenuated the development of hypertension in these animals.…”

Section: Discussionmentioning

confidence: 96%

Long-term intake of egg white hydrolysate attenuates the development of hypertension in spontaneously hypertensive rats

et al. 2006

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Section: Discussionmentioning

confidence: 96%

Long-term intake of egg white hydrolysate attenuates the development of hypertension in spontaneously hypertensive rats

et al. 2006

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“…The administration of Ca is paradoxically associated with a decrease in arterial blood pressure, and different studies carried out by our research group have also demonstrated that Caenriched diets can control hypertension in rats (López-Miranda et al 1998;Civantos et al 1999;Civantos Calzada & Aleixandre de Artiñano, 2003;Civantos & Aleixandre, 2004). Dietary Ca supplements also have beneficial effects in hypertensive patients (for reviews see Pryer et al 1995;Allender et al 1996;Resnick, 1999).…”

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confidence: 84%

Changes in arterial blood pressure in hypertensive rats caused by long-term intake of milk fermented by Enterococcus faecalis CECT 5728

Miguel

Muguerza²,

Sánchez³

et al. 2005

Br J Nutr

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We have evaluated the changes in arterial blood pressure caused in spontaneously hypertensive rats (SHR) by long-term intake of an Enterococcus faecalis CECT 5728-fermented milk with significant angiotensin-converting enzyme (ACE)-inhibitory activity. After being weaned, male 3-week-old SHR were randomized into five groups. Until the 20th week of life, rats in each group were given one of the following drinking fluids: tap water (negative control 1), a fermented milk without ACE-inhibitory activity (negative control 2), captopril (100 mg/kg) (positive control), the E. faecalis CECT 5728-fermented milk that had significant ACE-inhibitory activity, or Ca-enriched E. faecalis CECT 5728-fermented milk. Animals in the different groups were then given tap water as drinking fluid from the 20th to 25th week of life. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured weekly in the rats, from the 6th to 25th week of life, by the tail-cuff method. A definite decrease in SBP and DBP could be observed in the rats treated with captopril and also in the rats that received the E. faecalis CECT 5728-fermented milks. The greatest antihypertensive effect was observed when the pharmacological treatment was administered. The effect of the Ca-enriched fermented milk was slightly more accentuated and more constant than the effect of the E. faecalis CECT 5728-fermented milk that had not been enriched in Ca. SBP and DBP increased in the treated SHR when the corresponding antihypertensive treatment was removed. Fermentation of milk with E. faecalis CECT 5728 may therefore be a successful strategy to produce a functional food with antihypertensive activity.

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“…To minimize the effects of stress and its impact on blood pressure, the rats were accustomed to training sessions for 3 to 4 days before blood pressure measurements. Blood pressure was measured using the tail-cuff method in the conscious state as previously reported (8). These procedures were performed in a quiet, dark place and at the same time of day to avoid the influence of the circadian rhythm.…”

Section: Methodsmentioning

confidence: 99%

A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats

Othman

Suh²,

Fischer³

et al. 2008

American Journal of Physiology-Heart and Circulatory Physiology

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α-Adrenoceptor-mediated pressor responses in pithed rats fed diets with different calcium contents

Cited by 10 publications

References 42 publications

Long-term intake of egg white hydrolysate attenuates the development of hypertension in spontaneously hypertensive rats

Long-term intake of egg white hydrolysate attenuates the development of hypertension in spontaneously hypertensive rats

Changes in arterial blood pressure in hypertensive rats caused by long-term intake of milk fermented by Enterococcus faecalis CECT 5728

A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats

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