“…Here, we have reported a moderate/low density of immunoreactive fibres containing beta‐endorphin (1–27) in the area postrema, locus coeruleus, reticular formation, nucleus of the solitary tract, dorsal nucleus of the raphe and the periaqueductal gray. This means that the peptide could be involved in the control of pain transmission, sleep–waking cycle, taste, feeding, respiratory, cardiovascular, vigilance and stress mechanisms (Cerritelli, Hirschberg, Hill, Balthasar, & Pickering, ; de Freitas, Medeiros, & Khan, ; Li et al., ; Lima, Leite, Bethea, & Anselmo‐Franci, ).…”