The discovery and synthesis of vitamin C has made possible a significant advance in calcium therapy sufficient to warrant reexamination of the value of calcium therapy in otolaryngology.Vitamin C possesses the unique property of solubilizing and ionizing calcium to a degree not previously attainable by oral or intramuscular administration. In calcium cevitamate, the calcium salt of vitamin C, there is available a more effective approach to calcium therapy than that of the previously used gluconate.