Zur Ossifikation Allogener Lösungsmittelkonservierter Ossikeltransplantate. Vergleichende Histomorphologische Untersuchungen Im Tierexperiment Und an Humanen Explantaten.

Pesch, H.-J.; Behbehani, A. A.; Mees, K.

doi:10.1515/bmte.1989.34.s1.175

Cited by 3 publications

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“…Diese Umbauvorgänge wurden als Ausdruck der im Transplantat wirksam werdenden mechanischen Kräfte interpretiert, die mit Hilfe des Mukoperiosts eine Anpassung des avitalen Binde-und Stützgewebes an die biomechanische Beanspruchung induzierten [109,120,121]. Im Kaninchenmittelohr ließen sich rege Umbauvorgänge nachweisen.…”

Section: Definition Transplantat -Implantatunclassified

Materialien zur Rekonstruktion des Schalleitungsapparats

1999

HNO

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To rehabilitate most cases of conductive hearing loss closure of ear drum perforations and rebuilding of the ossicular chain can be performed. Due to the great number of biocompatible bone substitute materials available it is occasionally difficult for the surgeon to choose the most favorable substitute. Autogenous structures (ossicles, cortical bone, cartilage) and allogenous tissues (ossicles, cortical bone, cartilage, dentin) are possible bone replacement materials. Xenogenic tissue is currently not used in middle ear surgery. Ionomer cement is a hybrid material for replacement of bone but does not fit direct classification of the various classes of alloplastic materials in current use: that is, metals (gold, steel wire, platinum, titanium), plastics (polyethylene, polytetrafluorethylene) and ceramics (ceramic oxide, carbon, calcium-phosphate ceramic, vitreous ceramic). For restoration of the sound conductive apparatus preference is given to autogenous ossicles because cortical bone is resorbed and cartilage weakens over time. Most surgeons do not use allogenous tissue, because of the possible transmission of such infectious disease as immunodeficiency syndrome or Creutzfeldt-Jakob disease. Only dentin deserves special attention as a possible bone substitute in the middle ear because its form can be preserved during sterilization. Based on the observations available to date, it becomes apparent that titanium implants hold greater promise than gold. Form-stable synthetic materials are not generally recommended due to foreign body reactions which have been confirmed by many investigators. Ceramic materials (e.g. ceramic oxide, carbon, calcium-phosphate ceramic, glass ceramic) are well tolerated in the middle ear and have also proved to be useful over time. Hybrid bone substitute ionomer cement is easily workable and well integrated, showing a good functional outcome. For many years good results in otosclerosis surgery have been achieved with a prosthesis made of platinum-wire and Teflon. Short-term follow-up periods hold great promise with pistons made of gold. Autogenous ossicles, ionomer cement and recently titanium protheses--as far as usable--are employed by the author for reconstructing the middle ear. For the time being platinum-Teflon prostheses and gold are used in otosclerosis surgery.

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Section: Definition Transplantat -Implantatunclassified

Materialien zur Rekonstruktion des Schalleitungsapparats

1999

HNO

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Geh�rkn�chelchentransplantate zur Wiederherstellung der Schallleitungskette

2003

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Reconstruction of Orbital Floor Fracture Using Solvent-Preserved Bone Graft

Yavuzer

Tuncer

Basterzï

et al. 2004

Plastic and Reconstructive Surgery

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The orbital floor is one of the most frequently damaged parts of the maxillofacial skeleton during facial trauma. Unfavorable aesthetic and functional outcomes are frequent when it is treated inadequately. The treatment consists of spanning the floor defect with a material that can provide structural support and restore the orbital volume. This material should also be biocompatible with the surrounding tissues and easily reshaped to fit the orbital floor. Although various autografts or synthetic materials have been used, there is still no consensus on the ideal reconstruction method of orbital floor defects. This study evaluated the applicability of solvent-preserved cadaveric cranial bone graft and its preliminary results in the reconstruction of the orbital floor fractures. Twenty-five orbital floor fractures of 21 patients who underwent surgical repair with cadaveric bone graft during a 2-year period were included in this study. Pure blowout fractures were determined in nine patients, whereas 12 patients had other accompanying maxillofacial fractures. Of the 21 patients, 14 had clinically evident diplopia (66.7 percent), 12 of them had enophthalmos (57.1 percent), and two of them had gaze restriction preoperatively. Reconstruction of the floor of the orbit was performed following either the subciliary or the transconjunctival approach. A cranial allograft was placed over the defect after sufficient exposure. The mean follow-up period was 9 months. Postoperative diplopia, enophthalmos, eye motility, cosmetic appearance, and complications were documented. None of the patients had any evidence of diplopia, limited eye movement, inflammatory reactions in soft tissues, infection, or graft extrusion in the postoperative period. Providing sufficient orbital volume, no graft resorption was detected in computed tomography scan controls. None of the implants required removal for any reason. Enophthalmos was seen in one patient, and temporary scleral show lasting up to 3 to 6 weeks was detected in another three patients. Satisfactory cosmetic results were obtained in all patients. This study showed that solvent-preserved bone, which is a nonsynthetic, human-originated, processed bioimplant, can be safely used in orbital floor repair and can be considered as another reliable treatment alternative.

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Zur Ossifikation Allogener Lösungsmittelkonservierter Ossikeltransplantate. Vergleichende Histomorphologische Untersuchungen Im Tierexperiment Und an Humanen Explantaten.

Cited by 3 publications

References 1 publication

Materialien zur Rekonstruktion des Schalleitungsapparats

Materialien zur Rekonstruktion des Schalleitungsapparats

Geh�rkn�chelchentransplantate zur Wiederherstellung der Schallleitungskette

Reconstruction of Orbital Floor Fracture Using Solvent-Preserved Bone Graft

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