Zur Frage des endogenen Abbaues von Enzymen

Clinical Enzymology

“…Former studies have shown, that neither the removal of liver or spleen nor of the kidneys or the intestinal tract affects the elimination rates [38][39][40]42,56,57]. It was then believed that enzyme elimination might be a function of the reticule-endothelial system on the basis of indirect evidence before the era of labelled enzymes [37,42,44,58]. With 14C-acetylated LDH it was found that not the reticule-endothelial system but the parenchymal cells of most tissues are able to incorporate circulating enzyme molecules.…”