Zur Frage der Übertragung des thyreotropen hormons durch die Placenta und die Milch

THE PROBLEM OF PLACENTAL PERMEABILITY FOR THYROTROPHIN, PROPYLTHIOURACIL AND THYROXINE IN THE GUINEA PIG1

“…This conclusion is consistent with the opinions of several investigators who have studied one or more aspects of the subject (Freiesleben and Kjerluf-Jensen, 1947, for the goitrogen methylthiouracil in the rat; Aron, 1930, Schittenhelm and Eisler, 1935, Grumbrecht and Loeser, 1938, for TSH in the guinea pig; Grumbrecht andLoeser, 1938, Theresa, 1939, for thyroid hormone in the guinea pig and rabbit).…”

“…It is presumed from the work of D'Angelo and Gordon (1950) on the female guinea pig that production of TSH by the maternal pituitary would thus be released from inhibition and elevate the level of circulating TSH. The level of TSH can be further raised by injection of this hormone.…”