Zirconocene-Induced Cocyclisation/Elimination Reactions of 2-Heterosubstituted 1,6-Dienes and 1,6-Enynes

Abstract

Zirconocene-mediated cocyclisation of 2-heterosubstituted-1,6-dienes and -enynes gave zirconacycles bearing an endocyclic b-leaving group which eliminated under the reaction conditions to provide exocyclic alkylidene groups. The scope of this cyclisation/elimination has been investigated along with further elaboration of the monosubstituted zirconocene intermediates by insertion of alkenyl carbenoids.