“…In cells zinc is localized in membranous organelles (vesicles, Golgi apparatus). Its excessive release from such reserves threatens cytoplasmic enzymes its toxicity (Ward et al, 2000). Ligands-chelators (Frederickson, 2003), ionophores (Ho et al, 2004;Ding et al, 2008Ding et al, , 2009 are used to bind the excessive labile zinc.…”