Zinc deficiency in an exclusively breast-fed preterm infant

Heinen, Florian; Matern, Dietrich; Pringsheim, W; Leititis, J. U.; Brandis, M.

doi:10.1007/bf01972977

Cited by 37 publications

(31 citation statements)

References 41 publications

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“…Results of previous investigations have suggested that Zn deficiency in rapidly growing very-low-birth-weight infants is mainly associated with an increase of Zn requirements imposed by rapid growth and an inadequate intake [1][2][3]14]. As shown in table 2, the estimated Zn intake in the infants fed preterm human milk is lower than that using the four types of preterm formula available in Japan [16].…”

Section: Discussionmentioning

confidence: 99%

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Incidence and Predicting Factors of Hypozincemia in Very-Low-Birth-Weight Infants at Near-Term Postmenstrual Age

Itabashi

Saito²,

Ogawa³

et al. 2003

Neonatology

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We prospectively investigated serum zinc (Zn) concentrations and clinical factors in 118 very-low-birth-weight infants with a gestational age of 29.5 ± (SD) 2.5 weeks and a birth weight of 1,194 ± 254 g at near-term postmenstrual age. The 25th percentile of the serum Zn concentration was 7.0 µmol/l. The infants whose serum Zn concentrations were less than 7.0 µmol/l (defined as hypozincemia) did not have apparent symptoms of Zn deficiency. Multivariate logistic regression analyses demonstrated that hypozincemia was associated with factors such as weight gain (1-g/kg/day increase of weight; OR 1.1762, 95% CI 1.0414–1.3286) and serum albumin concentration (1-g/dl increase of serum albumin; OR 0.0816, 95% CI 0.0152–0.4372). The types of milk feeding did not affect the serum Zn concentrations in the study subjects. This study suggests that hypozincemia in very-low-birth-weight infants at near-term postmenstrual age is associated with greater weight gain and lower serum albumin concentration. Nutritional supply of Zn by human milk fortifier and preterm formula does not appear to meet the demands of rapidly growing very-low-birth-weight infants.

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Section: Discussionmentioning

confidence: 99%

“…The features of severe Zn deficiency include: dermatitis, diarrhea, alopecia, poor bone mineralization, increased susceptibility to infections, and growth retardation. Zn deficiency has been described in preterm infants [1][2][3][4]. Preterm infants have smaller fetal stores and a high nutritional demand.…”

Section: Introductionmentioning

confidence: 99%

Incidence and Predicting Factors of Hypozincemia in Very-Low-Birth-Weight Infants at Near-Term Postmenstrual Age

Itabashi

Saito²,

Ogawa³

et al. 2003

Neonatology

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“…ACQUIRED ZINC DEFICIENCY Acquired zinc deficiency finding and symptoms are similar to those of acrodermatitis enteropathica.In several papers,acquired zinc deficiency is reported due to lack of zinc in breast-milk with classical clinical findings of acrodermatitis enteropathica 10,11,12,13 . In these cases,since zinc absorbtion is normal,good treatment response is indicated 10,14 .…”

Section: Selenium Metabolismmentioning

confidence: 99%

Nütrisyonel Hastalıkların Deri Bulguları

Terzi

Akyol

2016

J Contemp Med

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Nutritional disease is caused by nutrient deficiency or, less commonly, by nutrient excess. Nutritional deficiency results from inadequate intake, impared absorbtion, defective metabolism of specific nutrients, or improper utilization.Cutaneous findings in nutritional disease can be very specific such as scurvy, pellegra. However the skin findings are often nondiagnostic.. Keywords:Nutritional disease, cutaneous, manifestation

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“…28 Human milk fortification The fortification of human milk can be performed by the use of a liquid commercial preterm infant formula mixed with an equal volume of human milk. Alternatively, a powdered commercial product may be used and prepared according to manufacturer's instructions.…”

Section: Zincmentioning

confidence: 99%