Yeast cell templated porous hollow silica spheres for rapid hemostasis accompanied by antibacterial action

Shi, Yuting; Yu, F. Richard; Liang, Xiaoqin; Huang, Congshu; Liang, Yu; Zheng, Yang; Yu, Jianping; Wang, Jianrong; Zhao, Guanghui

doi:10.1039/d2bm01619b

Cited by 6 publications

(4 citation statements)

References 27 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…70 Shi et al prepared a yeast cell templated porous hollow silica spheres (Ag@HMSNs) with a porous structure, a negatively charged surface, and an enlarged specific surface area that determine their good hemostatic properties. 71 In addition, Ag@HMSNs have excellent bactericidal effects due to the presence of Ag.…”

Section: Inorganic Hemostatic Materialsmentioning

confidence: 99%

“…Moreover, their tertiary stacked pores provided active sites for Ca 2+ to make full contact with coagulation factors to trigger the coagulation cascade reaction, and provided a stable environment for adsorption of plasma proteins to maintain activity for a longer time (Figure A) . Shi et al prepared a yeast cell templated porous hollow silica spheres (Ag@HMSNs) with a porous structure, a negatively charged surface, and an enlarged specific surface area that determine their good hemostatic properties . In addition, Ag@HMSNs have excellent bactericidal effects due to the presence of Ag.…”

Section: Inorganic Hemostatic Materialsmentioning

confidence: 99%

See 1 more Smart Citation

Recent Advances in Topical Hemostatic Materials

Liu,

Zhang,

Yao

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Untimely or improper treatment of traumatic bleeding may cause secondary injuries and even death. The traditional hemostatic modes can no longer meet requirements of coping with complicated bleeding emergencies. With scientific and technological advancements, a variety of topical hemostatic materials have been investigated involving inorganic, biological, polysaccharide, and carbonbased hemostatic materials. These materials have their respective merits and defects. In this work, the application and mechanism of the major hemostatic materials, especially some hemostatic nanomaterials with excellent adhesion, good biocompatibility, low toxicity, and high adsorption capacity, are summarized. In the future, it is the prospect to develop multifunctional hemostatic materials with hemostasis and antibacterial and anti-inflammatory properties for promoting wound healing.

show abstract

Section: Inorganic Hemostatic Materialsmentioning

confidence: 99%

Section: Inorganic Hemostatic Materialsmentioning

confidence: 99%

Recent Advances in Topical Hemostatic Materials

Liu,

Zhang,

Yao

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…It contains polar silanol groups on its surface, which can effectively promote blood coagulation [135]. The researchers used this structure to adsorb silver ions onto yeast to simulate diatomaceous earth cells and wrapped mesoporous silicon around the yeast to create silver-coated porous hollow silica spheres [136]. The resulting complex significantly improved blood hemostasis efficiency, reducing blood coagulation time by 290 s compared to the blank control group.…”

Section: Wound Care Techniques Inspired By Diatom and Diatomitementioning

confidence: 99%

Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin

Youn,

Ki,

Abdelhamid

et al. 2024

Biomimetics

View full text Add to dashboard Cite

Biomimetic materials have become a promising alternative in the field of tissue engineering and regenerative medicine to address critical challenges in wound healing and skin regeneration. Skin-mimetic materials have enormous potential to improve wound healing outcomes and enable innovative diagnostic and sensor applications. Human skin, with its complex structure and diverse functions, serves as an excellent model for designing biomaterials. Creating effective wound coverings requires mimicking the unique extracellular matrix composition, mechanical properties, and biochemical cues. Additionally, integrating electronic functionality into these materials presents exciting possibilities for real-time monitoring, diagnostics, and personalized healthcare. This review examines biomimetic skin materials and their role in regenerative wound healing, as well as their integration with electronic skin technologies. It discusses recent advances, challenges, and future directions in this rapidly evolving field.

show abstract

“…In various societal accidents, numerous wounded people die due to massive hemorrhage and ineffective hemostasis [1][2][3]. The development of hemostatic materials with various active components and in different forms to achieve more efficient hemostasis in wound healing has continued to increase during long-term studies [4][5][6][7]. These commercial hemostatic materials include kaolinite, which is used in combat gauze from Z-Medica Corp. (Wallingford, CT, USA); zeolite, which is used in QuikClot from Z-Medica Corp.; montmorillonite, which is used in WoundStat from TraumaCure Inc. (Bethesda, MD, USA); mesoporous silicon and chitosan, which are used in TraumaStat from Ore-Medix Inc. (Salem, OR, USA); chitosan, which is used in Celox from MedTrade Inc. (Houston, TX, USA) and ChitoGauze Pro from HemCon Inc. (Portland, OR, USA); and cellulose, which is used in Traumastem from Bioster Inc. (Stillwater, MN, USA) [8].…”

Section: Introductionmentioning

confidence: 99%

Clays and Wound Healing

Tian,

Wang,

Huang

et al. 2024

Materials

View full text Add to dashboard Cite

Aluminosilicates, such as montmorillonite, kaolinite, halloysite, and diatomite, have a uniform bidimensional structure, a high surface-to-volume ratio, inherent stiffness, a dual charge distribution, chemical inertness, biocompatibility, abundant active groups on the surface, such as silanol (Si-OH) and/or aluminol (Al-OH) groups. These compounds are on the list of U.S. Food and Drug Administration-approved active compounds and excipients and are used for various medicinal products, such as wound healing agents, antidiarrheals, and cosmetics. This review summarizes the wound healing mechanisms related to the material characteristics and the chemical components. Numerous wound dressings with different active components and multiple forms have been studied. Then, medicinal mineral resources for use in hemostatic materials can be developed.

show abstract

Yeast cell templated porous hollow silica spheres for rapid hemostasis accompanied by antibacterial action

Abstract: Uncontrolled haemorrhage is the leading cause in nearly 91 % of pre-hospital deaths which were considered potentially survivable. Particularly severe trauma is susceptible to infection, which further affects the natural...

Cited by 6 publications

References 27 publications

Recent Advances in Topical Hemostatic Materials

Recent Advances in Topical Hemostatic Materials

Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin

Clays and Wound Healing

Contact Info

Product

Resources

About