Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia

Antonelli, Massimo; Azoulay, Élie; Bonten, Marc J. M.; Chastre, Jean; Citerio, Giuseppe; Conti, Giorgio; Backer, Daniel De; Lemaire, François; Gerlach, Herwig; Groeneveld, Johan; Hedenstierna, Göran; MacRae, Duncan; Mancebo, Jordi; Maggiore, Salvatore Maurizio; Mebazaa, Alexandre; Metnitz, Philipp; Pugin, Jérôme; Wernerman, Jan; Zhang, Haibo

doi:10.1007/s00134-008-1371-6

Cited by 12 publications

(16 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The American College of Critical Care Medicine practice guidelines for pediatric and neonatal septic shock have recognized a threshold of 10% volume overload as a key time to act, although they do not specify interventions [18]. The clinical significance of fluid overload has also been demonstrated in adult patients with sepsis [19], respiratory distress syndrome [20, 21], and acute kidney injury [22–25]. …”

Section: Introductionmentioning

confidence: 99%

Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

et al. 2011

View full text Add to dashboard Cite

Purpose In pediatric intensive care unit (PICU) patients, fluid overload (FO) at initiation of continuous renal replacement therapy (CRRT) has been reported to be an independent risk factor for mortality. Previous studies have calculated FO based on daily fluid balance during ICU admission, which is labor intensive and error prone. We hypothesized that a weight-based definition of FO at CRRT initiation would correlate with the fluid balance method and prove predictive of outcome. Methods This is a retrospective single-center review of PICU patients requiring CRRT from July 2006 through February 2010 (n = 113). We compared the degree of FO at CRRT initiation using the standard fluid balance method versus methods based on patient weight changes assessed by both univariate and multivariate analyses. Results The degree of fluid overload at CRRT initiation was significantly greater in nonsurvivors, irrespective of which method was used. The univariate odds ratio for PICU mortality per 1% increase in FO was 1.056 [95% confidence interval (CI) 1.025, 1.087] by the fluid balance method, 1.044 (95% CI 1.019, 1.069) by the weight-based method using PICU admission weight, and 1.045 (95% CI 1.022, 1.07) by the weight-based method using hospital admission weight. On multivariate analyses, all three methods approached significance in predicting PICU survival. Conclusions Our findings suggest that weight-based definitions of FO are useful in defining FO at CRRT initiation and are associated with increased mortality in a broad PICU patient population. This study provides evidence for a more practical weight-based definition of FO that can be used at the bedside.

show abstract

Section: Introductionmentioning

confidence: 99%

Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

et al. 2011

View full text Add to dashboard Cite

show abstract

“…We relinquished the chance to examine a correlation between ISP and ONSD values, as sufficient evidence of a correlation with raised intracranial pressure already exists …”

Section: Discussionmentioning

confidence: 99%

Sonographic Changes in Optic Nerve Sheath Diameter Associated with Supra‐ versus Infrarenal Aortic Aneurysm Repair

Ertl

Schierling

Kasprzak

et al. 2016

Journal of Neuroimaging

View full text Add to dashboard Cite

show abstract

“…It is likely that the higher proportion of patients with mtDNA haplogroup R who showed neurological recovery would, at least partly, contribute to the global clinical outcome of severe sepsis. Since septic encephalopathy is a set of alterations in consciousness ranging from mild stupor to coma [27] and recovery is a slow process, some patients may still show mental deterioration even when their GCS score reaches 15. However the trend for neurological variation of septic encephalopathy can be implied from GCS score determination.…”

Section: Discussionmentioning

confidence: 99%

Mitochondrial DNA haplogroup R in the Han population and recovery from septic encephalopathy

et al. 2011

View full text Add to dashboard Cite

In the Han population, mtDNA haplogroup R is a strong independent predictor of the outcome of septic encephalopathy, conferring an increased chance of neurological recovery compared with individuals with a non-R haplogroup. Our results provide potential insights into the mechanisms involved in septic encephalopathy, and reveal that the mtDNA haplogroup R is an independent predictor of the outcome of septic encephalopathy.

show abstract

Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia

Abstract: Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia

Cited by 12 publications

References 87 publications

Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy

Sonographic Changes in Optic Nerve Sheath Diameter Associated with Supra‐ versus Infrarenal Aortic Aneurysm Repair

Mitochondrial DNA haplogroup R in the Han population and recovery from septic encephalopathy

Contact Info

Product

Resources

About