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Beutler, William; Fredrickson, Bruce E.; Murtland, Albert; Sweeney, Colleen; Grant, William E.; Baker, D. N.

doi:10.1097/00007632-200305150-00014

Cited by 43 publications

(34 citation statements)

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“…In the present study we found that males had statistically significantly higher prevalence of spondylolysis (p=0.0354). The male-to-female ratio of almost 3:1 in the current study is just slightly higher than 2:1 ratio reported in other studies 25–29 . Women demonstrated a significantly higher prevalence of degenerative spondylolisthesis compared to men (p=0.008), with a male-to-female ratio of 1:3.…”

Section: Discussioncontrasting

confidence: 79%

Spondylolysis and Spondylolisthesis

Kalichman

Kim²,

Li³

et al. 2009

Spine

306

105

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Study Design Cross-sectional study. Objectives 1) to determine prevalence rates of spondylolysis, isthmic and degenerative spondylolisthesis in an unselected adult community-based population; 2) to evaluate the association of spondylolysis, isthmic and degenerative spondylolisthesis with low back pain (LBP). Summary of Background Data Spondylolysis and spondylolisthesis are prevalent in the general population; however the relationship between these conditions and LBP is controversial. Methods This study was an ancillary project to the Framingham Heart Study. A sample of 3529 participants of the Framingham Heart Study aged 40–80 years underwent multi-detector CT imaging to assess aortic calcification. 188 individuals were consecutively enrolled in this study to assess radiographic features potentially associated with LBP. The occurrence of LBP in the preceding 12 months was evaluated using a self-report questionnaire. The presence of spondylolysis and spondylolisthesis was characterized by CT imaging. We used multiple logistic regression models to examine the association between spondylolysis, spondylolisthesis and LBP, while adjusting for gender, age and BMI. Results 21 study subjects demonstrated spondylolysis on CT imaging. The male-to-female ratio was approximately 3:1. 21% of subjects with bilateral spondylolytic defects demonstrated no measurable spondylolisthesis. The male-to-female ratio of degenerative spondylolisthesis was 1:3, and the prevalence of degenerative spondylolisthesis increased from the fifth through eight decades of life. 38 subjects (20.4%) reported significant LBP. No significant association was identified between spondylolysis, isthmic spondylolisthesis, or degenerative spondylolisthesis, and the occurrence of LBP. Conclusions Based on CT imaging of an unselected community-based population, the prevalence of lumbar spondylolysis is 11.5%, nearly twice the prevalence of previous plain radiograph-based studies. This study did not reveal a significant association between the observation of spondylolysis on CT and the occurrence of LBP, suggesting that the condition does not appear to represent a major cause of LBP in the general population.

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Section: Discussioncontrasting

confidence: 79%

Spondylolysis and Spondylolisthesis

Kalichman

Kim²,

Li³

et al. 2009

Spine

306

105

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“…This was observed in our study, where approximately more than 45% of patients with spondylolysis did not develop spondylolisthesis. Other authors have also reported a similar finding: up to 55% of patients diagnosed with spondylolysis did not progress to spondylolisthesis [212223]. …”

Section: Discussionsupporting

confidence: 60%

Facture of the Pars Interarticularis with or without Spondylolisthesis in an Adult Population in a Developing Country: Evaluation by Multidetector Computed Tomography

et al. 2017

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Study DesignDescriptive cross-sectional study.PurposeTo determine the prevalence of lumbar spondylolysis and spondylolisthesis in a general adult population unrelated to lower back pain as evaluated by multidetector computed tomography.Overview of LiteratureThere is a significant paucity of information related to the prevalence of spondylolysis and spondylolisthesis and its degenerative changes in a general adult population unrelated to lower back pain in developing countries.MethodsA retrospective study was conducted on abdominopelvic computed tomography (CT) scans performed between January 1st 2015 and December 31st 2015 for various clinical indications. Patients with lower back pain, with a history of trauma or road traffic accident, or referred from orthopedic or neurosurgery departments were excluded to avoid any bias. CT scans were reviewed in axial, sagittal, and coronal planes using bone window settings for evaluating spondylolysis and spondylolisthesis.ResultsOf 4,348 patients recruited, spondylolysis and spondylolisthesis were identified in 266 (6.1%) and 142 (3.3%) patients, respectively. Age was significantly higher in both spondylolysis and spondylolisthesis patients than in those without spondylolysis and spondylolisthesis (47.19±15.45 vs. 42.5±15.96, p<0.001 and 53.01±15.31 vs. 42.44±15.88, p<0.001, respectively). Gender was significantly associated with spondylolisthesis (p=0.029) but not spondylolysis. Of patients who were >60 years old, both spondylolysis (p=0.018) and spondylolisthesis (p=0.025) were significantly more prevalent in females.ConclusionsThe prevalence of pars interarticularis fracture observed higher with gradual increase in the prevalence with advancing age. In particular, preponderance was significantly higher among older females.

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“…However, the male-to-female ratio was almost 2:1 in previous studies 1,11-13). Waldron14) suggested in 1991 that the difference in incidence between genders may be a rather recent phenomenon.…”

Section: Discussionmentioning

confidence: 90%

Prevalence of Spondylolysis and Its Relationship with Low Back Pain in Selected Population

Lee

2011

Clin Orthop Surg

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BackgroundTo determine the prevalence of spondylolysis in a selected population and evaluate the association of spondylolysis with low back pain (LBP). Spondylolysis is widespread in the general population but the prevalence of spondylolysis and its relationship with LBP in the Korean population is controversial.MethodsA sample of 855 participants (age, 20 to 86 years) from our medical center who underwent multidetector computed tomography (CT) imaging to assess abdominal and urological lesions were enrolled in this study. The occurrence of LBP requiring medication in the preceding 12 months was evaluated using a self-report questionnaire (a modified Nordic Low Back Pain Questionnaire). The presence of spondylolysis was characterized by CT imaging. Multiple logistic regression models were used to examine the association between spondylolysis and LBP, while adjusting for gender and age.ResultsSeventy-eight study subjects (9%) demonstrated spondylolysis on CT imaging. There was no significant difference between the age groups (p = 0.177). The p-value of gender was 0.033 but this was not significant due to the selected population bias. Three hundred eleven study subjects (36%) had back pain. There was a significant difference between gender (p = 0.001). No significant association was identified between spondylolysis and the occurrence of LBP.ConclusionsThe prevalence of LBP was 36.37% and the prevalence of lumbar spondylolysis in a selected population, who visited hospital for abdominal or urological lesions except LBP, was 9.12% based on CT imaging. Males demonstrated a similar presence of LBP to females but a significantly higher incidence of spondylolysis (p = 0.033). The prevalence of spondylolysis was not associated with the presence of LBP and age in adulthood.

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Cited by 43 publications

References 0 publications

Spondylolysis and Spondylolisthesis

Spondylolysis and Spondylolisthesis

Facture of the Pars Interarticularis with or without Spondylolisthesis in an Adult Population in a Developing Country: Evaluation by Multidetector Computed Tomography

Prevalence of Spondylolysis and Its Relationship with Low Back Pain in Selected Population

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