XC.—Indican. Part II

Evaluation of Lens Aldose Reductase Inhibitory and Free Radical Scavenging Potential of Fractions of Lonchocarpus cyanescens: Potential for Cataract Remediation

“…20 The plant has alternate leaves and flat fruits which are 1 -5 seeded, oblong pod pointed at both ends. 19,21,22 The aerial parts yield an indigo, which is a useful colourant for cloth dyeing [adire/gara] in West Africa since ancient times 23 Some of the reported medicinal uses of the plant include poultice to treat skin diseases and ulcers (leaves and roots); possible cure for leprosy (leaves and roots); laxative (leaves); intestinal disorders and dysentery (leaf sap); diarrhea, aphrodisiac, veneral diseases and athritis (decoction of leafy twigs and roots); yaws and sores (ground root). 5 Bioactivity effects of Lonchocarpus cyanescens have also been demonstrated in its anti-inflammatory, anti-arthritic and its relief on ulcer.…”

Dyes, Natural

“…Indican [487- is the dextrose derivative (35) of indoxyl [480-93-3] (110). Indoxyl occurs also in the urine of humans as the potassium salt of indoxyl sulfonic acid (111).…”

Synthesis and Autoxidation of New Tetracyclic 9H,10H-Indolizino[1,2-b]indole-1-ones

“…9 Indole also undergoes autoxidation by PtO 2 and the C 2 -C 3 bond is subsequently cleaved to give the ring expanded product. 10 On the other hand, the C 2 -ethyl group of 2,3-diethylindole was reported to afford 2-acetyl-3-ethylindole via autoxidation. 11 Autoxidation is a slow atmospheric oxidation of a C-H bond to a C-OOH bond and occurs when the compound is allowed to stand in air and is catalyzed by light.…”

“…It is known that indole undergoes oxidation by air and light (autoxidation) to form indoxyl which can further form dimer or trimer . Indole also undergoes autoxidation by PtO 2 and the C 2 −C 3 bond is subsequently cleaved to give the ring expanded product . On the other hand, the C 2 -ethyl group of 2,3-diethylindole was reported to afford 2-acetyl-3-ethylindole via autoxidation …”