Xanthogranulome parotidien de l’adulte

Dhouib, H.; Hammami, B.; Sellami, M.; Mnif, Lilia; Boudawara, T.; Ghorbel, A.

doi:10.1016/j.stomax.2009.09.017

Cited by 3 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Juvenile xanthogranulomas of the external auditory canal 28 and parotid gland 29,30 have been rarely reported and have no specific appearance. Parotid JXG may cause diffuse glandular infiltration, as in one of our cases, or be a focal nodular lesion 31 . The main differential diagnoses of diffuse infiltration of the parotid glands, which is generally bilateral, are lymphoma, leukemia, HIV infection, and systemic disorders (Sjogren’s disease, sarcoidosis) (Fig.…”

Section: Discussionmentioning

confidence: 70%

See 1 more Smart Citation

Juvenile Xanthogranuloma of the Head and Neck: Imaging Findings in 11 Cases

Chalard,

Nguyen,

Morel

et al. 2024

Journal of Pediatric Hematology/Oncology

View full text Add to dashboard Cite

Background: Juvenile Xanthogranuloma (JXG) is a non-Langerhans cell histiocytosis, occurring mainly in infancy. With an extracutaneous lesion, its diagnosis is difficult, because of a wide clinical spectrum. Here we demonstrate and characterize imaging features of 11 patients with JXG of the head and neck in various locations. Material and Methods: We recorded clinical data and reviewed all imaging studies of 11 patients with JXG of the head and neck. Ultrasonography (US) alone was performed in 1 patient; MRI alone in 6 patients; US and MRI in 1 patient; and US, CT, and MRI in 3 patients. We evaluated the following characteristics in all studies: location and number of lesions, echogenicity and vascularization on US, density on CT, signal intensity on T1- and T2-weighted images, ADC and enhancement on MRI, and tumor boundaries and bone involvement. Results: Lesions were well-defined in 9 cases, and bone erosion was present in 2. On US, lesions were hypoechoic or hyperechoic and with or without vascularization. On CT, lesions were hyper-dense, with no calcification. On MRI, lesions were mildly hyper-intense or iso-intense on T1-weighted images in 8 of 9 patients, hypo-intense on T2-weighted images in 7 of 10, low ADC in 7 of 9, and enhancement in 7 of 7. Conclusions: The diagnosis of extra cutaneous JXG may be proposed, with the following suggestive criteria: age < 1 year, well-defined lesion, mild hyper-intensity on T1-weighted images, hypo-intensity on T2-weighted images, low ADC, enhancement, and possible adjacent bone involvement.

show abstract

Section: Discussionmentioning

confidence: 70%

“…Parotid JXG may cause diffuse glandular infiltration, as in one of our cases, or be a focal nodular lesion. 31 The main differential diagnoses of diffuse infiltration of the parotid glands, which is generally bilateral, are lymphoma, leukemia, HIV infection, and systemic disorders (Sjogren’s disease, sarcoidosis) (Fig. 10 A-D).…”

Section: Discussionmentioning

confidence: 99%

Juvenile Xanthogranuloma of the Head and Neck: Imaging Findings in 11 Cases

Chalard,

Nguyen,

Morel

et al. 2024

Journal of Pediatric Hematology/Oncology

View full text Add to dashboard Cite

show abstract

“…This disease most frequently occurs in the pediatric population, but one adult case with parotid involvement of juvenile xanthogranuloma has been reported. 22 JXG is frequently associated with a mixed inflammatory infiltrate that may contain a significant number of eosinophils and in early stages of the disease, lesional cells may display an absence of lipidized cytoplasm. Notably, multi-nucleated Touton giant cells are less prevalent at non-dermal sites.…”

Section: Discussionmentioning

confidence: 99%

A case of coexisting Warthin tumor and langerhans cell histiocytosis associated with necrosis, eosinophilic abscesses and a granulomatous reaction in intraparotid lymph nodes

2011

View full text Add to dashboard Cite

We present a patient (50-year-old male) with coexisting Warthin tumor and involvement of two intraparotid lymph nodes by Langerhans cell histiocytosis associated with necrosis, eosinophilic abscesses and a granulomatous reaction. This is the second documented case of this unusual combination of histological changes in nodal Langerhans cell histiocytosis and the first case involving intraparotid lymph nodes occurring together with an ipsilateral Warthin tumor.

show abstract