Xanthogranulomatous osteomyelitis of Tibia in a case of 43 years old male patient: A rare entity diagnosed in a tertiary care hospital

Abstract

Xanthogranulomatous inflammation is a form of chronic inflammatory process with collection of foamy macrophages in sheets, often with presence of giant cell reaction. Here, we present a case of xanthogranulomatous osteomyelitis of tibia in a 43 years old patient, which is a rare pathological entity and possibly was reported first in 1984. The histopathological sections revealed dense collection of lympho-plasmacytic infiltrate in the marrow spaces with syncytial sheets of foamy macrophages admixed with numerous classical Touton giant cells.