Xanthogranulomatous endometritis presenting as pyometra and mimicking carcinoma on imaging

Malik, Col Ajay; Dudani, Sharmila; Mani, Brig N S

doi:10.4103/0976-7800.185326

Cited by 6 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The cytoplasm is also rich in lipids or hemosiderin. There are also plasma cells, lymphocytes and neutrophils in the background ( 36 , 37 ). Unlike malacoplakia, these patients lack characteristic MG bodies.…”

Section: Discussionmentioning

confidence: 99%

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Li,

Mi,

Wang

et al. 2024

Front. Med.

View full text Add to dashboard Cite

Malacoplakia is a rare chronic granulomatous disease that mostly affects the gastrointestinal tract and urinary tract of immunocompromised patients; malacoplakia rarely effects the female reproductive tract. Here, we report a 56-year-old patient who underwent thymectomy for thymoma and myasthenia gravis prior to developing cervical and vaginal malacoplakia. The patient presented with recurrent vaginal bleeding. We discovered that there were alterations in the cervical cauliflower pattern during colposcopy, which is suggestive of cervical cancer. Pathological examination of the lesion tissue showed that a large number of macrophages aggregated, and M-G bodies with concentric circles and refractive properties were observed between cells. Immunostaining for CD68 and CD163 was positive, and special staining for D-PAS and PAS was positive. The discovery of Escherichia coli in bacterial culture can aid in the diagnosis of malacoplakia. Following surgery, we performed vaginal lavage with antibiotics in addition to resection of local cervical and vaginal lesions. This study provides a fresh perspective on the management of genital malacoplakia.

show abstract

Section: Discussionmentioning

confidence: 99%

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Li,

Mi,

Wang

et al. 2024

Front. Med.

View full text Add to dashboard Cite

show abstract

“…Necrosis of tumor cells following irradiation in cervical or endometrial carcinoma can also induce chronic inflammation with pyometra 8 . Histopathological examination of XGE is characterized by focal or total replacement of the endometrium by granulation tissue with presence of foamy histiocytes, variable numbers of multinucleated giant cells, chronic inflammatory cells, necrotic material, siderophages, calcium, and hemosiderin 9 . The infiltration of the myometrium by foamy macrophages might be misdiagnosed as clear cell carcinoma or sarcoma, but the cytological characteristic should lead to the XGE diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous endometritis: A case report and literature review

Merviel

James

Carlier

et al. 2021

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

“…It is mostly seen in patient with hematometra which is observed in our case. 14 Endometrial polyps are common, with their prevalence appearing to increase with age. In postmenopausal women, estrogen receptors are more prevalent in polyps than the adjacent normal endometrium, which may alter proliferative process, resulting in polyp formation.…”

Section: Discussionmentioning

confidence: 99%

Endometrial pathology in postmenopausal women: Analysis of 112 cases in tertiary care centre

Walke¹,

Datar²,

Kowe³

2020

PJMS

View full text Add to dashboard Cite

Background: Postmenopausal bleeding is a frequent finding accounting for 5-10% of women in gynaecology clinic. About 10% of these patients have primary or secondary malignancy. Aim: The histopathological patterns of endometrium, in postmenopausal women presenting with bleeding were studied along with the frequency of endometrial cancer. Materials and Methods: It was both a prospective and retrospective, observational study carried out over a period of one and half year in tertiary care teaching hospital on 112 postmenopausal women, above 40 year of age with history of one year of amenorrhoea without hormone replacement therapy. The samples were obtained by dilatation and curettage and endometrial pipelle procedure. Results and Discussion: Maximum patients belonged to age group of 46-50 year. The most common histopathological pattern observed was atrophic endometrium in 42 (37.5%) patients followed by simple hyperplasia in 13(11.6%) and endometrial polyp in 7(6.25%) cases. Irregular shedding of endometrium was diagnosed in 8 case (7.14%). The maximum patients of endometrial carcinoma (5.35 %) were noted in 61-65 age groups. Inflammatory pathology was found in 4(3.56%) and atypical hyperplasia was seen a single case (0.89%). In 8 cases, the opinion could not be offered due to inadequacy of sample. Conclusion:As the incidence of malignancy in postmenopausal period remains sufficiently high, it requires immediate investigation in the form of endometrial sampling for early diagnosis, prompt treatment and vigilant follow up.

show abstract

Xanthogranulomatous endometritis presenting as pyometra and mimicking carcinoma on imaging

Cited by 6 publications

References 7 publications

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Xanthogranulomatous endometritis: A case report and literature review

Endometrial pathology in postmenopausal women: Analysis of 112 cases in tertiary care centre

Contact Info

Product

Resources

About