1976
DOI: 10.1001/archderm.112.1.43
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Xanthogranuloma in adults

Abstract: Nine cases of cutaneous xanthogranuloma in adults are reported. These lesions were histologically indistinguishable from the xanthogranulomas in infants and children (juvenile xanthogranuloma), and, like those in the young, they were not associated with abnormalities of serum lipids. Unlike juvenile xanthogranuloma, however, in our small sample there was no concomitant involvement of the eye in adult xanthogranuloma.

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Cited by 42 publications
(30 citation statements)
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“…Thus, it does not require exhaustive investigations. Spontaneous involution seems more frequent than it was commonly believed [1, 4, 18] (54% vs. 83% in JXG), with a mean duration of 22 months; therefore, aggressive treatment should be avoided. The main differential diagnosis is with PX, which has the same clinical feature and evolution as AXG, occurring after young adolescence, in solitary or multiple form, with no extracutaneous localization except for mucosal involvement, and frequent spontaneous involution.…”
Section: Discussionmentioning
confidence: 99%
“…Thus, it does not require exhaustive investigations. Spontaneous involution seems more frequent than it was commonly believed [1, 4, 18] (54% vs. 83% in JXG), with a mean duration of 22 months; therefore, aggressive treatment should be avoided. The main differential diagnosis is with PX, which has the same clinical feature and evolution as AXG, occurring after young adolescence, in solitary or multiple form, with no extracutaneous localization except for mucosal involvement, and frequent spontaneous involution.…”
Section: Discussionmentioning
confidence: 99%
“…Half of the cases of JXG have been reported in infants less than six months of age. (1) Approximately 10% of JXGs manifest in adulthood, and this form of JXG has been conveniently termed 'late-onset JXG' by some authors. (2) The present case report describes an unusual presentation of JXG in a 28-year-old man.…”
Section: Introductionmentioning
confidence: 99%
“…It is predominantly a disease of infancy or early childhood, although adults may infrequently be affected (adult xanthogranuloma) [1,2], the histological findings of both forms being indistinguishable [1,3]. The lesions are characterized clinically by unique or multiple yellow-red papulonodules that usually regress spontaneously in children and tend to persist in adult xanthogranuloma [4,5].…”
Section: Introductionmentioning
confidence: 99%