X-ray phase-contrast computed tomography for full breast mastectomy imaging at the Australian Synchrotron

Arhatari, Benedicta D.; Nesterets, Yakov; Taba, Seyedamir Tavakoli; Maksimenko, Anton; Hall, Christopher; Stevenson, Andrew W.; Häusermann, Daniel M.; Lewis, Sarah; Dimmock, Matthew; Thompson, Darren; Mayo, Sheridan C.; Quiney, Harry M.; Gureyev, T. E.; Brennan, Patrick C.

doi:10.1117/12.2596225

Cited by 1 publication

(2 citation statements)

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“…The researchers reported that they were planning to perform clinical trials in association with related healthcare providers. [12][13][14] Refraction based tomographic SR imaging methods called X-ray dark field imaging CT (XDFI-CT) methods have been developed by M. Ando and his colleagues since the mid-1990s at Photon Factory (Tsukuba, Japan). Using a specially designed asymmetrically-cut monochromator and Laue angle analyzer, this technique could provide higher contrast and excellent spatial resolution from human soft tissue specimens without contrast or staining media.…”

Section: Introductionmentioning

confidence: 99%

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Imaging optimisation process of human lung tissue using synchrotron radiation microcomputed tomography in PLS‐II

et al. 2023

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Synchrotron radiation microcomputed tomography (SR‐μCT) can provide non‐destructive three‐dimensional investigation for soft tissue with high resolution. The aim of this study is to evaluate technical improvements in microcomputed tomographic imaging of human lung tissue using a synchrotron radiation source at the 6C biomedical beamline. SR‐μCT images of excised human lung tissue (6 mm vertically and 10 mm horizontally sized) were explored at the 6C biomedical beamline in the Pohang accelerator laboratory (Pohang, Republic of Korea) using phase retrieval methods with a modified Bronnikov algorithm. Experimental data collection was performed with changes in the following conditions: the presence of a graphite attenuator, sample to detector distance, the presence of different scintillators and increasing pixel sizes. We identified that the resolution of lung tissue images was sufficiently enhanced when the graphite attenuator was not applied, 550 mm of sample to detector distance, with Cadmium tungsten (CdWO4) scintillator and twice binning of the pixel data and could be comparable with images from pathologic examination. Refinement of SR‐μCT techniques for soft tissue originating from the human body would advance the potential clinical application of synchrotron radiation in the near future.

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Section: Introductionmentioning

confidence: 99%

“…The PB‐CT breast images from mastectomy specimens showed higher quality than that possible with other conventional medical imaging modalities. The researchers reported that they were planning to perform clinical trials in association with related healthcare providers 12–14 …”

Section: Introductionmentioning

confidence: 99%