X-Ray diffraction analysis of White ProRoot MTA and Diadent BioAggregate

Park, Jeong Won; Hong, Sunwook; Kim, Jong-Hyun; Lee, Seung-Jong; Shin, Su-Jung

doi:10.1016/j.tripleo.2009.08.039

Cited by 78 publications

(114 citation statements)

References 17 publications

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“…This could be attributed to the persistent infection and chronic inflammation. Both MTA and BioAggregate subgroups showed a significant lower mean inflammatory cell count than positive subgroup due to sealing ability, biocompatibility and alkaline pH on setting (Schwartz et al, 1999;Park et al, 2010). In addition, the closure of the access cavity prevents further infection at the furaction perforation.…”

Section: Discussionmentioning

confidence: 98%

“…Sci., 9 (4): 148-156, 2015 recently, new products similar to MTA have been introduced into the market including MTA Angelus and MTA Bio and BioAggregate (Zhang et al, 2009). BioAggregate appears to be a modified version of MTA; it is a new retrograde filling and root canal perforation repair material (Park et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Tantalum oxide acts as a radiopacifier instead of bismuth oxide which is present in MTA. The other difference between these two products is the presence of hydroxyapatite in BioAggregate (Park et al, 2010). Both MTA and BioAggregate have the same bactericidal effects on E. faecalis (Zhang et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

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Histologic Evaluation of Furcation Perforation Treated with Mineral Trioxide Aggregate and Bioaggregate

Hassanien¹,

Abu‐Seida²,

Hashem³

et al. 2015

Asian J. of Animal Sciences

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The aim of this work was to evaluate the healing of furcation perforation following treatment with Mineral Trioxide Aggregate (MTA) and BioAggregate by histologic examination. The present study was carried out on a total of 72 premolar teeth from 6 adult mongrel dogs. Under general anesthesia, furcation perforation was carried out by using a round bur # 4. The access cavity of all experimental and positive control teeth was left open for 4 weeks. The teeth were classified according to the observation period into three groups; I (one week), II (one month) and III (3 months) (2 dogs each). Each group was further subdivided into three subgroups according to the treatment protocol. These subgroups included; subgroup a (MTA), subgroup b (BioAggregate) and subgroup c (positive control). Inflammatory cell count, epithelial proliferation and new hard tissue formation were assessed. Statistical analysis of the results was carried out and significance of the parameters was determined in the tests at p<0.05. The statistical analysis revealed that MTA and BioAggregate had a similar biological response on the periodontal tissue. There was no significant difference in inflammatory cell count, epithelial proliferation and new hard tissue formation between MTA and BioAggregate subgroups. In conclusion, both MTA and Bioaggregate show similar biological responses when used as a perforation repair material in dogs. These responses showed improved healing characteristics when compared to the control.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

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Histologic Evaluation of Furcation Perforation Treated with Mineral Trioxide Aggregate and Bioaggregate

Hassanien¹,

Abu‐Seida²,

Hashem³

et al. 2015

Asian J. of Animal Sciences

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“…[9][10][11][12] Park et al examined the chemical composition of BioAggregate and reported that it contained a significant amount of tantalum oxide instead of bismuth oxide. 9 The major compo- 12 Bioaggregate appears to be a modified or synthetic version of original MTA. Since the clinical indications of Bioaggregate are the same as those of MTA, it might be helpful to compare this new material with MTA, which has already been studied and proven to be effective and biocompatible over the past few years.…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Chung

Kim

Shin

2010

J Korean Acad Conserv Dent

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Objectives: This study was performed to investigate the biocompatibility of newly introduced Bioaggregate on human pulp and PDL cells. Materials and Methods: Cells were collected from human pulp and PDL tissue of extracted premolars. Cell culture plate was coated either with Bioaggregate or white MTA, then the same number of cells were poured to cell culture dishes. Cell attachment and growth was examined under a phase microscope after 1,3 and 7 days of seeding. Cell viability was measured and the data was analyzed using Student t-test and one way ANOVA. Results: Both types of cells used in this study were well attached and grew healthy on Bioaggregate and MTA coated culture dishes. No cell inhibition zone was observed in Bioaggregate group. There was no statistical difference of viable cells between bioaggreagte and MTA groups. Conclusions: Bioaggregate appeared to be biocompatible compared with white MTA on human pulp and PDL cells.

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“…The major difference between MTA is that BioAggregate is aluminium-free and contains a significant amount of tantalum oxide instead of bismuth oxide and calcium phosphate. [30,31] This aluminium-free property might increase its biocompatibility.…”

Section: Microscopy Resultsmentioning

confidence: 99%

Evaluation of cytotoxicity and gelatinases activity in 3T3 fibroblast cell by root repair materials

Varol

Bahar

Karsli

et al. 2016

Biotechnology & Biotechnological Equipment

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The aim of this study was to investigate the effects of calcium silicate-based products on cytotoxicity in the 3T3 fibroblast and gelatinolytic activity of matrix metalloproteinases (MMPs). 3T3 fibroblasts were incubated directly with Ortho Mineral trioxide aggregate (MTA), BioAggregate, Biodentine, MTA Plus, MTA Angelus and MTA Cerkamed for 24 hours and seven days. The cytotoxicity was determined using an MTT assay. Supernatants were collected to determine MMP-2 and MMP-9. Data were analysed using IBM SPSS 22. Seventh day extracts of Ortho MTA and Biodentine showed reduced cell viability. Specific characterization of MMPs in cell culture demonstrated that MMP-2 (62 kPa) in the cell culture supernatants by gelatin zymography showed induced expression in four out of seven groups by 3T3 cells. No MMP-9 expression was observed. The cytotoxicity of materials revealed a significant difference in cell viability between the groups on the first and seventh days. The results of this study revealed minor cytotoxic effects for Ortho MTA and Biodentine. This study suggests that endodontic sealers induced production of MMP-2. MMP-9 might be expressed in small amounts when compared with MMP-2.

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X-Ray diffraction analysis of White ProRoot MTA and Diadent BioAggregate

Cited by 78 publications

References 17 publications

Histologic Evaluation of Furcation Perforation Treated with Mineral Trioxide Aggregate and Bioaggregate

Histologic Evaluation of Furcation Perforation Treated with Mineral Trioxide Aggregate and Bioaggregate

Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells

Evaluation of cytotoxicity and gelatinases activity in 3T3 fibroblast cell by root repair materials

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