X-Ray and theoretical structural study of novel 5,6,7,8-tetrahydrobenzo-4H-pyrans

Synthesis and <i>in vitro</i> antimicrobial evaluation of 5-amino-7-aryl-6-cyano-4<i>H</i>- pyrano[3,2,<i>b</i>]pyrrole derivatives catalyzed by reusable ZrOCl₂•8H₂O

“…All yields refer to isolated products unless otherwise stated. 1 H NMR (500 MHz) and 13 C NMR (125 MHz) spectra were obtained using Bruker DRX-500 Avance at ambient temperature, using TMS as internal standard. FT-IR spectra were obtained as KBr discs on Shimadzu spectrometer.…”

“…Some of these compounds are widely employed as cosmetics and pigments and as potential biodegradable agrochemicals [12]. Furthermore, they play a significant role as potential calcium channel antagonists which are structurally similar to biologically active 1,4-dihydropyridines [13]. Therefore, the synthesis of such compounds has attracted strong interest.…”

Synthesis of a novel 4H-pyran analog as minor groove binder to DNA using ethidium bromide as fluorescence probe

“…A number of 2-amino-4H-pyrans are widely utilized in cosmetics, pigments, and also act as potential biodegradable agrochemicals [13]. Some of the 4H-pyran derivatives are used as photoactive materials [14] and potential calcium channel antagonists [15]. Furthermore, 4H-pyrans are structural units in series of natural products [16].…”

A facile and efficient protocol for the synthesis of 2-amino-3-cyano-4H-pyran derivatives at ambient temperature

“…Polysubstituted 4H-pyrans also constitute a structural unit of many natural products 11,12 . 4H-Pyran derivatives are also potential calcium channel antagonists, 13 which are structurally similar to biologically active 1,4-dihydropyridines (1,4-DHPs).…”