Wound Healing and Scarring of the Developing Filtering Bleb — A Major Challenge in Glaucoma Surgery

Objective Evaluation of Functionality of Filtering Bleb Based on Polarization-Sensitive Optical Coherence Tomography

“…Hence, the inhibition of wound healing is an indication of successful filtration surgery. 2,3 Despite recent improvements in surgical techniques, [4][5][6] fibrosis is inevitable in the long-term, and a good monitoring scheme is required to optimize the reintervention and followup medication. The current follow-up modalities include color photography, 7 slit-lamp examination, 7 ultrasound biomicroscopy (UBM), 8 in vivo confocal microscopy, 8 and anterior segment optical coherence tomography (AS-OCT).…”

Standardization of the dose of intraoperative mitomycin C in trabeculectomy

“…The main challenge that remains is, however, the lack of predictability of postoperative wound healing and scar formation at the filtering site [1]. The most common reason for failure is scarring of the subconjunctival connective tissue, at the level of the conjunctiva-Tenon's capsuleepiscleral interface.…”