Wound Healing after Xenon Arc Photocoagulation in the Rabbit Retina

Inomata, Hajime

doi:10.1159/000307253

Cited by 27 publications

(2 citation statements)

References 3 publications

(3 reference statements)

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“…Another mechanism which has been postulated is cell division of RPE cells. This has been shown in rabbits after photocoagulation [9], in monkeys after retinal detachment [10] and in rabbits after surgically induced RPE defects [8]. It is unclear whether cell division can also occur in aged RPE cells of patients with macular degeneration.…”

Section: Patientmentioning

confidence: 97%

Variability of RPE reaction in two cases after selective RPE laser effects in prophylactic treatment of drusen

Roider

Brinkmann²,

Wirbelauer

et al. 1999

Graefe's Archive for Clinical and Experimental Ophthalmology

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Section: Patientmentioning

confidence: 97%

Variability of RPE reaction in two cases after selective RPE laser effects in prophylactic treatment of drusen

Roider

Brinkmann²,

Wirbelauer

et al. 1999

Graefe's Archive for Clinical and Experimental Ophthalmology

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“…Regarding its mechanism of action, FLP acts to seal the area that leaks, which is most commonly associated with RPE irregularities and leaking PED 15 . Experimental studies indicate that adjacent RPE cells expand to cover the gaps created by laser treatment, restoring the RPE barrier 16 . When comparing a cohort of CSC patients after FLP treatment to those following the natural course of CSC, the authors observed a more rapid resolution 5 , 17 , 18 and a lower likelihood of recurrence in the treated patients 19 .…”

Section: Discussionmentioning

confidence: 99%

Effective Focal Laser Photocoagulation for Persistent Central Serous Chorioretinopathy: A Forgotten Technique

Kiraly

2023

Klin Monbl Augenheilkd

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We report a case of a patient with persistent central serous chorioretinopathy (CSC) who was on the waiting list for half-dose photodynamic therapy (PDT). As the patient's visual function began to deteriorate, patient opted for focal laser photocoagulation (FLP) targeting the presumed leakage site in the superior part of the macula. One month after the FLP treatment, there was complete resolution of SRF accompanied by improved visual function. In light of global verteporfin shortages, limited access to PDT centers, and poor efficacy from other treatment modalities, FLP emerges as an effective treatment option for CSC patients with extrafoveal leakage. Yet, many CSC patients with extrafoveal leakage, who could be effectively treated with FLP, are often merely monitored, experiencing fluctuating SRF and a gradual, irreversible vision decline. Despite FLP's historical presence in CSC treatment, our case serves as an important reminder for retinal specialists to reconsider this treatment approach in selected CSC patients.

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