Wound dressing following primary total hip arthroplasty: a prospective randomised controlled trial

Siddiqui, MA; Bidaye, A; Baird, Emily; Abu-Rajab, R.; Stark, A; Jones, Bryn; Ingram, Roland; Anthony, Iain

doi:10.12968/jowc.2016.25.1.40

Cited by 14 publications

(13 citation statements)

References 12 publications

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“…No significant results for the additional application of cyanoacrylate glue on the incidence of SSIs were reported from the RCT (Table and Figure ). Siddiqui et al reported an increase in SSI in the intervention group (SSI = 3) in comparison with the control group ( SSI = 1) ( P = 0.62).…”

Section: Resultsmentioning

confidence: 96%

“…Wound closure with subcuticular sutures and subsequent application of cyanoacrylate glue was used in the intervention arm of all included articles. Siddiqui et al further dressed the wound with Opsite in both arms (United Kingdom) . Ozturk et al compared subcuticular sutures and antibiotic ointment with or without cyanoacrylate glue.…”

Section: Resultsmentioning

confidence: 99%

“…Definitions of SSI for each of the included articles were accepted. Siddiqui et al defined SSI as patient‐reported infection requiring a course of antibiotics prescribed by a general practitioner. Grimaldi et al defined SSI by the presence of symptoms and positive clinical findings (erythema, pain, and colour of the wound).…”

Section: Resultsmentioning

confidence: 99%

“…No significant results for the additional application of cyanoacrylate glue on the incidence of SSIs were reported from the RCT (Table 3 and Figure 3). Siddiqui et al 14 reported an increase in SSI in the intervention group (SSI = 3) in comparison with the control group (SSI = 1) (P = 0.62). Grimaldi et al 15 (n = 900) reported a significant reduction in SSI in the intervention group (SSI n = 6) in comparison with the control group (SSI n = 18) (P = 0.03).…”

Section: Incidence Of Ssimentioning

confidence: 95%

“…A single article assessed the use of cyanoacrylate glue in clean-contaminated cases in paediatric circumcision surgery. 16 The remaining two articles undertaken in adults examined the use of cyanoacrylate glue in clean cases: total hip replacement 14 and cosmetic surgery (abdominoplasties, breast augmentation, dermolipectomy, and scar revision). 15 Wound closure with subcuticular sutures and subsequent application of cyanoacrylate glue was used in the intervention arm of all included articles.…”

Section: Study Characteristicsmentioning

confidence: 99%

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Systematic review of the use of cyanoacrylate glue in addition to standard wound closure in the prevention of surgical site infection

Machin

Liu

Coupland

et al. 2018

International Wound Journal

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Surgical site infection (SSI) is associated with increased morbidity, length of stay, and cost. Cyanoacrylate glue is a low‐cost, fluid‐proof, antimicrobial barrier. The aim of this systematic review is to assess the use of cyanoacrylate glue after standard wound closure versus dressings in the reduction of SSI. Medline, Embase, Cochrane Library, and clinical trial registries were searched with no restrictions in accordance with PRISMA guidelines. Eligibility criteria were prospective studies comparing glue versus dressings after standardised wound closure. Two reviewers independently screened articles and utilised GRADE for quality assessment. Meta‐analysis was not performed because of the heterogeneity of the data. Three articles were included in the review. Study quality was uniformly low. Incidence of SSI was low, between 0% and 4%. No significant differences were reported in the single randomised controlled trial. A single non‐randomised parallel group trial reported a significant reduction in the incidence of SSI in the cyanoacrylate group. There was no consistent evidence demonstrating reduction in SSI as a result of the use of cyanoacrylate glue. Future studies should assess the use of cyanoacrylate in procedures with a higher rate of SSI, for example, lower limb bypass.

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Section: Resultsmentioning

confidence: 96%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Incidence Of Ssimentioning

confidence: 95%

Section: Study Characteristicsmentioning

confidence: 99%

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