World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestation on dogs and cats

Marchiondo, Alan A.; Holdsworth, Pa; Green, P.; Blagburn, Byron L.; Jacobs, D. Ε.

doi:10.1016/j.vetpar.2006.10.028

Cited by 182 publications

(113 citation statements)

References 35 publications

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“…The three groups each consisted of three males and five female cats and thus with 8 animals per group exceeded the requirements of the World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P. ), "Guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestations on dogs and cats" of at least six animals per group (Marchiondo et al 2013). All cats were dewormed and did not harbour ticks or fleas at the commencement of the study.…”

Section: Animalsmentioning

confidence: 99%

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Comparative Speed of Kill, Repellent (anti-feeding) and Acaricidal Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and a Fipronil/(S)-Methoprene/Eprinomectin/Praziquantel Spot-on (Broadline®) against Ixodes ricinus (Linné, 1758) on Cats

et al. 2015

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Speed of kill, repellent (anti-feeding) and acaricidal efficacy of an imidacloprid 10 % (w/w) /flumethrin 4.5 % (w/w) collar (Seresto ® , Bayer) and a spot-on formulation of fipronil 8.3 % (w/v) /(S)-methoprene 10 % (w/v) /eprinomectin 0.4 % (w/v) /praziquantel 8.3 % (w/v) (Broadline ® , Merial) against artificiallyinduced infestations with Ixodes ricinus on cats, were assessed in a parallel group design, randomised, controlled study. Twenty-four cats were included and randomly allocated to treatment groups or a non-treated control group. Starting on Day (D) 7 after treatment until D28, cats were each infested with 50 I. ricinus at weekly intervals. Ticks were counted in situ on the cats at 6, 12 and 24 h and upon removal 48 h after each infestation.Based on arithmetic means, Seresto ® proved to be 100 % effective against adult I. ricinus at all assessment times (6, 12, 24 and 48 h after infestation) throughout the month-long study. Broadline ® was 0 % to 16.7 % effective at 6 h, 26.8 % to 50.0 % effective at 12 h, while at 24 h after infestation efficacy peaked at 81.5 % on D15 declining to 31.5 % on D29. Based on the 48 h tick counts, the efficacy of Broadline ® peaked at 100 % on D16 after treatment and decreased to 83.2 % by D30. The Seresto ® collar provided significantly faster speed of kill and better persistent acaricidal effectiveness against Ixodes ricinus on cats compared to Broadline ® spot-on. The additional repellent (anti-feeding) effect of Seresto ® prevents parasites from taking a blood meal and thereby reduces the risk of vector-borne disease pathogen transmission. S109ECtopar aSItES

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Section: Animalsmentioning

confidence: 99%

“…Live free or attached ticks were considered treatment failures (Marchiondo et al 2013). The primary assessment norm was the number of ticks counted on the untreated control and the two treated groups of cats at the various assessment times and days, with efficacy calculations based on arithmetic means.…”

Section: Tick Countsmentioning

confidence: 99%

Comparative Speed of Kill, Repellent (anti-feeding) and Acaricidal Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and a Fipronil/(S)-Methoprene/Eprinomectin/Praziquantel Spot-on (Broadline®) against Ixodes ricinus (Linné, 1758) on Cats

et al. 2015

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“…The days of 'flea powder' as the mainstay of ectoparasite control are long past, and dog owners have a wide variety of insecticidal and acaricidal sprays, 'spot-ons', dips, rinses and shampoos, orally administered tablets, and chemically-impregnated collars to choose from. Such products contain not only pulicides and acaricides, some also contain insect growth regulators (IGRs), or insect development inhibitors (IDIs) that exert their action by interfering with the development of the eggs or other off-host life-cycle stages, and some have repellent agents (e.g., permethrin) that discourage arthropods from attaching to the host [76].…”

Section: Paradigm 5: Prevention Is Better Than Curementioning

confidence: 99%

It shouldn’t happen to a dog … or a veterinarian: clinical paradigms for canine vector-borne diseases

Irwin

2014

Trends in Parasitology

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Keywords:Canine, vector-borne diseases, zoonosis, emerging disease, diagnosis, travel medicine, compliance AbstractCanine vector-borne diseases (CVBDs) comprise a diverse group of viral, bacterial, protozoal, and helminth pathogens, transmitted predominantly by ticks and fleas, and cause significant health problems for dogs worldwide. Growing numbers of reports indicate that CVBDs are emerging in regions where they previously did not exist and this, combined with pathogens that are inherently difficult to detect, is providing companion animal veterinarians with some significant diagnostic challenges. This review discusses six paradigms concerning the diagnosis, treatment, prevention, and zoonotic implications of CVBDs from a veterinary clinical perspective. Veterinarians are the key professionals at the companion animal: human interface. Not only do they provide the traditional medical and surgical services for pets, their training in the disciplines of parasitology, microbiology, epidemiology, and public health place them in a unique position to provide advice about matters pertaining to vector-borne diseases. Despite this, emerging canine vector-borne diseases (CVBDs) pose a number of significant and complex challenges for veterinarians in clinical practice whose responsibility it is to diagnose and treat these companion animals, while at the same time remaining mindful of the potential for disease transmission to the owners and other people living in close proximity, as well as to other susceptible animals [5]. As will be discussed here, many CVBDs are caused by organisms that are inherently difficult to detect, frequently cause nebulous clinical signs in their canine hosts, and are sometimes zoonotic. In addition, the rapid progress of scientific research in this area itself poses further challenges of how best to distil and disseminate this knowledge to busy veterinary practitioners worldwide at a time when every aspect of clinical practice is becoming more complex. How should practitioners keep current with information in this area so that they can provide appropriate evidence-based advice to their clients?

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“…The ticks were counted in situ and classified, but left in place at the 24 h and 48 h post infestation tick counts and removed at the 72 h count. The ticks remaining on the placebo dogs 72 h post infestation on Days 98, 112 and 196 were not removed until the following tick challenge, to re-stimulate these dogs' Marchiondo et al (2007) immunity to holocyclotoxin. Acaricidal efficacy was calculated using geometric mean numbers of ticks, as recommended by Marchiondo et al (2007):…”

Section: Assessing Efficacymentioning

confidence: 99%

Long-Term Efficacy of an Imidacloprid 10 % / Flumethrin 4.5 % Polymer Matrix Collar (Seresto®, Bayer) against the Australian Paralysis Tick (Ixodes holocyclus) in Dogs

2013

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Two placebo-controlled pen studies were conducted to assess the efficacy of an imidacloprid 10 %/flumethrin 4.5 % polymer matrix collar (Seresto ® , Bayer; Investigational Veterinary Product (IVP)) against the Australian paralysis tick (Ixodes holocyclus). Dogs assigned to the placebo (n = 8) or IVP (n ≥ 8) groups had collars (placebo or IVP) attached on Day 0 and were infested with 30 unfed, adult, female I. holocyclus at 14-28 day intervals over 227 days.

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World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestation on dogs and cats

Cited by 182 publications

References 35 publications

Comparative Speed of Kill, Repellent (anti-feeding) and Acaricidal Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and a Fipronil/(S)-Methoprene/Eprinomectin/Praziquantel Spot-on (Broadline®) against Ixodes ricinus (Linné, 1758) on Cats

Comparative Speed of Kill, Repellent (anti-feeding) and Acaricidal Efficacy of an Imidacloprid/Flumethrin Collar (Seresto®) and a Fipronil/(S)-Methoprene/Eprinomectin/Praziquantel Spot-on (Broadline®) against Ixodes ricinus (Linné, 1758) on Cats

It shouldn’t happen to a dog … or a veterinarian: clinical paradigms for canine vector-borne diseases

Long-Term Efficacy of an Imidacloprid 10 % / Flumethrin 4.5 % Polymer Matrix Collar (Seresto®, Bayer) against the Australian Paralysis Tick (Ixodes holocyclus) in Dogs

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