Work-related stress and depressive disorders

Tennant, Christopher

doi:10.1016/s0022-3999(01)00255-0

Cited by 466 publications

(348 citation statements)

References 89 publications

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“…Several studies confirmed the pathogenic effects of stress and strain at work for mental health (e.g., Larisch et al, 2003;Niedhammer et al, 1998;Tennant, 2001;Tsutsumi et al, 2001;Wang & Patten, 2001). However, the present study extends previous research because it is one of the few using established diagnoses for mental disorders based on a standardized interview.…”

Section: Discussionsupporting

confidence: 80%

“…Thus the question arises whether there are also work-related risk factors for developing mental disorders. In a review of prospective studies, Tennant (2001) concluded that workrelated stress contributes to depressive symptoms in several occupations. The author underlines the adverse effects of increasing demands and job insecurity as a growing problem among workers.…”

Section: Introductionmentioning

confidence: 99%

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Work and mental disorders in a German national representative sample

2006

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Most previous studies concerning the associations between work and mental ill-health have used dimensional self-report questionnaires for mental health problems (e.g., depressive symptoms). This study contributes to occupational health research by providing standardized clinical diagnoses based on DSM-IV criteria. A total of 2329 employees (age 18 Á65 years) took part in a structured, computer-assisted clinical interview (DIA-X/M-CIDI). Further, they specified whether their job was characterized by physical workload, overtime, or stress, and evaluated whether they feel impaired by each job characteristic. Results show that substance abuse/dependence (including nicotine dependence) was the highest prevalent mental disorder in German employees (12 month prevalence: 14.4%; only alcohol and illicit substance abuse/dependence: 4.9%) followed by anxiety (12.0%) somatoform (9.7%), and affective (9.3%) disorders. Sequential logistic regression analyses showed significant associations between the presence of stress at work and affective and somatoform disorders. Furthermore, feeling impaired by stress at work was strongly associated with anxiety, affective, somatoform disorders, and substance abuse/dependence. Beside work, personal characteristics, primarily gender, were associated with mental disorders in employees. However, except for affective disorders, gender did not modify the association between job characteristics and mental disorders. Taken together, results corroborate the necessity of considering mental disorders at work. Further studies to define the relation between work and mental disorders in employees are strongly recommended and should include objective analyses of job characteristics.

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Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Work and mental disorders in a German national representative sample

2006

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“…Os resultados mostraram que essas alterações são mais frequentes nos professores que informaram uso de medicamentos para depressão/ansiedade, pequena ou razoável possibilidade de serem criativos, pouco ou razoável tempo para preparação de aulas, vivência de episódio de agressão na escola, relatos compatíveis com disfonia e exposição a ruído elevado e insuportável. Tennant (2001) esclarece os tipos de transtornos psíquicos relacionados ao trabalho. Em sua maioria, estão presentes quadros depressivos, nervosismo, abuso de bebidas alcoólicas, sintomas físicos sem explicação e cansaço mental, com sérias consequências para o desempenho profissional e impacto cada vez mais forte na função familiar, além de serem responsáveis por elevados custos sociais.…”

Section: Dimensões Da Intensificação Do Trabalho Docenteunclassified

Intensificação do trabalho e saúde dos professores

Assunção¹,

Oliveira²

2009

Educ. Soc.

124

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RESUMO:A centralidade atribuída aos docentes nos processos de reformas educacionais em curso traz novas exigências profissionais com efeitos sobre a sua saúde. Buscando resultados na literatura epidemiológica e ergonômica, este artigo tece relações entre o processo de intensificação do trabalho nas escolas e o tipo de adoecimento dos professores descrito nos estudos atuais. Sobre a intensificação, são mencionados fatores qualitativos, caracterizados pelas transformações da atividade sem o necessário suporte social para acomodar as exigências do trabalho, e fatores quantitativos, relacionados ao aumento do volume de tarefas nas escolas. As evidências trazidas ao texto permitem esboçar as bases de um modelo explicativo para o processo de morbidade docente calcado em determinantes ambientais e organizacionais e suas implicações sobre a atividade de trabalho na sala de aula. Palavras-chave:Intensificação do trabalho. Saúde do trabalhador.Trabalho docente. Professor. WORK INTENSIFICATION AND TEACHERS' HEALTHABSTRACT: The centrality given to teachers in the ongoing educational reforms creates new professional demands that affect their health. Seeking results in the literature on epidemiology and ergonomics, this paper suggests relations between the work * Doutora em Ergonomia, médica do trabalho e professora

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“…Social stress and economic pressure are most common in western societies and largely increase the risk of psychopathologies (Tennant, 2001). Animal models of social stress, including chronic social defeat stress (CSDS), are widely used to model this situation in rodents and are accepted models for key clinical symptoms of depression (Savignac et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Differences in FKBP51 Regulation Following Chronic Social Defeat Stress Correlate with Individual Stress Sensitivity: Influence of Paroxetine Treatment

Wagner

Marinescu

Hartmann

et al. 2012

Neuropsychopharmacol

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Various clinical studies have identified FK506-binding protein 51 (FKBP51) as a target gene involved in the development of psychiatric disorders such as depression. Furthermore, FKBP51 has been shown to affect glucocorticoid receptor signaling by sensitivity modulation and it is implicated in stress reactivity as well as in molecular mechanisms of stress vulnerability and resilience. We investigated the physiological, behavioral, and neuroendocrine parameters in an established chronic stress model both directly after stress and after a recovery period of 3 weeks and also studied the efficacy of paroxetine in this model. We then examined FKBP51 mRNA levels in the dorsal and ventral part of the hippocampus and correlated the expression to behavioral and endocrine parameters. We show robust chronic stress effects in physiological, behavioral, and neuroendocrine parameters, which were only slightly affected by paroxetine treatment. On the contrary, paroxetine led to a disruption of the neuroendocrine system. FKBP51 expression was significantly increased directly after the stress period and correlated with behavioral and neuroendocrine parameters. Taken together, we were able to further elucidate the role of FKBP51 in the mechanisms of stress resilience and vulnerability, especially with respect to behavioral and neuroendocrine parameters. These findings strongly support the concept of FKBP51 as a marker for glucocorticoid receptor sensitivity and its involvement in the development of psychiatric disorders.

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Work-related stress and depressive disorders

Cited by 466 publications

References 89 publications

Work and mental disorders in a German national representative sample

Work and mental disorders in a German national representative sample

Intensificação do trabalho e saúde dos professores

Differences in FKBP51 Regulation Following Chronic Social Defeat Stress Correlate with Individual Stress Sensitivity: Influence of Paroxetine Treatment

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