Wooden-tip electrospray ionization mass spectrometry for trace analysis of toxic and hazardous compounds in food samples

Abstract

Wooden-tip electrospray ionization (wooden-tip ESI) is applied to the rapid, in situ, direct qualitative and quantitative trace analysis of toxic and hazardous compounds in food samples. To evaluate the potential of wooden-tip ESI mass spectrometry (MS) in food analysis, pesticides, toxicants, date-rape drugs, and illicit additives were detected in various food samples. Wooden-tip ESI-MS experiments were performed using wooden tip sampling and ionization, with examination using MS and tandem mass spectrometry (MS/MS). The results proved that wooden-tip ESI allows the detection and confirmation of traces of toxic and hazardous compounds in food. In addition, selected analytes in beverages were obtained at absolute levels as low as $10 pg. Quantitation of analytes in liquid and powder samples was also evaluated. Single sample analysis was completed within 2 min. The data obtained shows that the wooden-tip ESI-MS is a promising tool for rapid analysis of food samples.

Principles and applications of solid-substrate electrospray ionization mass spectrometry

“…http://engine.scichina.com/doi/10.1360/N032017-00116 Yang等 [122] 采用木签电喷雾电离质谱检测了果汁中的 高效氯氰菊酯残留, 检测限为30 ng/mL. 在兽药残留检测方面, Zhang等 [123] 采用纸喷雾 电离质谱直接检测了肉类中的多种兽药包括克伦特 罗、特布他林、沙丁胺醇和多巴胺等, 检测限达到 1.0~5.0 ng/g.…”

“…Zhang等 [123] 采用纸喷雾电离 质谱检测了辣椒粉中添加的苏丹红II, III, IV和G, 牛奶 中的三聚氰胺, 以及饮料中的塑化剂, 取得了满意结 果. 在食物中有毒物质方面, Yang等 [122] 采用木签电喷 雾电离质谱筛查了火锅中多种有毒生物碱, 以及饮料 中的精神药物, 检出限为30 ng/mL.…”

Rapid and sensitive detection of trace malachite green and its metabolite in aquatic products using molecularly imprinted polymer-coated wooden-tip electrospray ionization mass spectrometry

“…Ambient MS gives such an opportunity. During the past two decades, a series of ambient ionization techniques, such as desorption electrospray ionization (DESI), 12 extractive electrospray ionization (EESI), [13][14][15] direct analysis in real time (DART), [16][17][18] probe electrospray ionization (PESI), 19,20 lowtemperature plasma (LTP), 21,22 desorption corona beam ionization (DCBI), 23,24 laser ablation electrospray ionization (LAESI), [25][26][27] paper spray, [28][29][30][31][32] and wooden-tip ESI have been developed, [33][34][35][36][37][38][39][40] which facilitate rapid, direct and straightforward analysis of various samples under ambient and open-air conditions with minimal or no sample pretreatment. However, MG and its metabolite usually present in the environment or aquatic products with a trace level of concentrations (around the mg L À1 level), and the compositions of matrices are also unknown with complexities.…”

Fast quantitation of pyrazole fungicides in wine by ambient ionization mass spectrometry

“…31 LOQs obtained ranged between 1 and 100 ng/mL for pesticides and 10 and 250 ng/mL for different adulterants. Other examples include the use of paper spray for analyzing herbicides 32 , wooden-tip electrospray ionization (ESI) for toxic and hazardous compounds in food samples, 33 thermal desorption ESI for pesticide residuals in food stuff, 34 and DESI for distribution of pesticides on leaf surfaces. 35 LTP was also previously used to detect five classes of fungicides, 36 but excluding the pyrazole fungicides.…”